EMAIL THIS PAGE TO A FRIEND
72779 Sigma

Irgasan

≥97.0% (HPLC)

Synonym: 5-Chloro-2-(2,4-dichlorophenoxy)phenol, Irgasan, Triclosan

  • CAS Number 3380-34-5

  • Empirical Formula (Hill Notation) C12H7Cl3O2

  • Molecular Weight 289.54

  •  Beilstein Registry Number 2057142

  •  EC Number 222-182-2

  •  MDL number MFCD00800992

  •  PubChem Substance ID 57652433

Purchase

Properties

Related Categories A - K, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics G-M,
biological source   from synthetic
material   colorless or white
InChI Key   XEFQLINVKFYRCS-UHFFFAOYSA-N
assay   ≥97.0% (HPLC)
form   powder
ign. residue   ≤0.1%
mp   56-58 °C
solubility   H2O: soluble12 g/L at 20 °C
Mode of action   enzyme | inhibits

Description

Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Application

A component of cefsulodin-irgasan-novobiocin selection medium for Yersinia, a human pathogen that may contaminate animal-source food products. Because of its low antigenicity, irgasan is also a component of many antibacterial consumer products.

Biochem/physiol Actions

Irgasan is a broad spectrum antimicrobial agent. It is an inhibitor of the enoyl-ACP (acyl-carrier protein) reductase component of type II fatty acid synthase (FAS-II) in bacteria and Plasmodium. It also inhibits mammalian fatty acid synthase (FASN), and may have anticarcinogenic activity.

Packaging

5, 25 g in poly bottle

Price and Availability


Discover the Milli-Q® IQ 7000 ultrapure water system
Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
RTECS 
KO1100000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Determination of Triclosan in Environmental Waters

Introduction Triclosan is a chemical that has been used as an antibacterial agent in many soaps and a variety of other consumer and personal care products for many years. Because of its widespread us...
Olga Shimelis, Michael Halpenny, Ken Espenschied, Kristen Schultz
Reporter US Volume 32.2
Keywords: Adsorption, Detection methods, Environmental, High performance liquid chromatography, Mass spectrometry, Pharmaceutical, Sample preparations, Separation, Solid phase extractions

Fatty Acid Synthesis and Metabolism in Cancer Cells

Proliferatively active cells require fatty acids for functions such as membrane generation, protein modification, and bioenergetic requirements. These fatty acids are derived either from dietary sour...
Keywords: Apoptosis, Biofiles, Cancer, Carboxylations, Catalysis, Citric Acid Cycle, Gene expression, Glycolysis, Metabolism, Oxidations, PAGE, Phosphorylations

Peer-Reviewed Papers
15

References

Set your institution to view full text papers.
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?