EMAIL THIS PAGE TO A FRIEND
72779 Sigma

Irgasan

≥97.0% (HPLC)

Synonym: 5-Chloro-2-(2,4-dichlorophenoxy)phenol, Irgasan, Triclosan

Purchase

Properties

Related Categories A - K, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics G-M,
biological source   from synthetic
InChI Key   XEFQLINVKFYRCS-UHFFFAOYSA-N
assay   ≥97.0% (HPLC)
form   powder
ign. residue   ≤0.1%
color   colorless to white
mp   56-58 °C
solubility   H2O: 12 g/L at 20 °C
Mode of action   enzyme | inhibits
antibiotic activity spectrum   fungi

Description

Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Application

A component of cefsulodin-irgasan-novobiocin selection medium for Yersinia, a human pathogen that may contaminate animal-source food products. Because of its low antigenicity, irgasan is also a component of many antibacterial consumer products.

Biochem/physiol Actions

Irgasan is a broad spectrum antimicrobial agent. It is an inhibitor of the enoyl-ACP (acyl-carrier protein) reductase component of type II fatty acid synthase (FAS-II) in bacteria and Plasmodium. It also inhibits mammalian fatty acid synthase (FASN), and may have anticarcinogenic activity.

Packaging

5, 25 g in poly bottle

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
RTECS 
KO1100000

Documents

Certificate of Analysis

Certificate of Origin

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis. These documents are located on the product detail page under Useful Links & Tools. Click on the following link to search for a Certificate of Analysis. Please click the following link to see the details on our Product Dating Information.
How do I get lot-specific information or a Certificate of Analysis?
A Certificate of Analysis is available by lot number and can be obtained through our Advanced Search Option: http://www.sigmaaldrich.com/catalog/AdvancedSearchPage.do
What is Product 72779, Irgasan, soluble in?
Per The Merck Index, 12th edition, Entry# 9790, Irgasan is not soluble in water, but it is readily soluble in alkaline solutions and many organic solvents.
What are other names besides Irgasan that Product 72779 may be referred to?
Irgasan may also be referred to as Triclosan and 5-Chloro-2-(2,4-dichlorophenoxy)phenol.  See http://www2.sigmaaldrich.com/catalog/search/ProductDetail/FLUKA/72779
How do I find price and availability?
There are several ways to find pricing and availability for our products.  Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers. 
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS. To access the shipping information for this material, use the link on the product detail page for the product, or search here. 
My question is not addressed here, how can I contact Technical Service for assistance?
Use the option to the right to "Ask a Question" by email of a Technical Service Scientist.
Show more questions
Protocols & Articles

Articles

Determination of Triclosan in Environmental Waters

Introduction Triclosan is a chemical that has been used as an antibacterial agent in many soaps and a variety of other consumer and personal care products for many years. Because of its widespread us...
Olga Shimelis, Michael Halpenny, Ken Espenschied, Kristen Schultz
Reporter US Volume 32.2
Keywords: Adsorption, Detection methods, Environmental, High performance liquid chromatography, Mass spectrometry, Pharmaceutical, Sample preparations, Separation, Solid phase extractions

Fatty Acid Synthesis and Metabolism in Cancer Cells

Proliferatively active cells require fatty acids for functions such as membrane generation, protein modification, and bioenergetic requirements. These fatty acids are derived either from dietary sour...
Keywords: Apoptosis, Biofiles, Cancer, Carboxylations, Catalysis, Citric Acid Cycle, Gene expression, Glycolysis, Metabolism, Oxidations, PAGE, Phosphorylations

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?