Nourseothricin sulfate
≥85% (HPLC)
DOWNLOAD MSDS (PDF)-
CAS Number 96736-11-7
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MDL number MFCD00165013
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Popular Documents: Datasheet (PDF)
Properties
| Related Categories | Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics N-S, Antibiotics by Application, |
| assay | ≥85% (HPLC) |
| storage temp. | 2-8°C |
Description
Biochem/physiol Actions
Antifungal effective against Candida albicans. Candida species transformed with the gene encoding nourseothricin acetyltransferase (CaNAT1) were resistant to nourseothricin.1
Nourseothricin inhibits biosynthesis and induces miscoding. Resistance to nourseothricin is mediated by the sat1 encoded N-acetyltransferase. Nourseothricin is inactivated by acetylation of the β-amino group of the β-lysin.
Application
Noursethricin is used as a dominant selection antibiotic for genetically modified bacteria, yeasts, fungi, protozoa and plants.
Price and Availability
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