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75633 Sigma

Osmium tetroxide solution

for electron microscopy, 2% in H2O

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Properties

Related Categories Chemical Synthesis, Osmium, Oxidizing Agents, Synthetic Reagents
grade   for electron microscopy
InChI Key   VUVGYHUDAICLFK-UHFFFAOYSA-N
concentration   2% in H2O
density   1.0 g/mL at 20 °C
  1.0 g/mL at 20 °C
storage temp.   2-8°C

Description

Application

Osmium tetroxide solution has been used as a fixative in electron microscopy.

Biochem/physiol Actions

Osmium tetroxide is also referred to as osmium and is mainly used as a secondary fixative of tissues. The molecule reacts with lipid moieties and is responsible for the oxidation of unsaturated bonds of fatty acids. This reaction adds density and contrast to biological samples. In normal tissues, presence of osmium results in intense black staining which can be viewed by normal eye. In addition, it can be used as a mordant (a molecule which combines with stain or dye at later stages) in electron microscopy, thereby enhancing lead staining.

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.



Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 3287 6.1 / PGII
WGK Germany 
1
Protocols & Articles
Peer-Reviewed Papers
15

References

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