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76200 Sigma

D-Panthenol

≥98.0% (NT)

Synonym: (R)-(+)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide, (R)-2,4-Dihydroxy-3,3-dimethylbutyric 3-hydroxypropylamide, D-Pantothenyl alcohol, Dexpanthenol, Provitamin B

  • CAS Number 81-13-0

  • Empirical Formula (Hill Notation) C9H19NO4

  • Molecular Weight 205.25

  •  Beilstein Registry Number 1724947

  •  EC Number 201-327-3

  •  MDL number MFCD00065006

  •  PubChem Substance ID 57652627

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Properties

Related Categories Amides, Asymmetric Synthesis, Biochemicals and Reagents, Chemical Synthesis, Chiral Building Blocks,
InChI Key   SNPLKNRPJHDVJA-ZETCQYMHSA-N
assay   ≥98.0% (NT)
optical activity   [α]20/D +30±1°, c = 5% in H2O
impurities   ≤0.002% heavy metals
  ≤0.5% 3-aminopropanol
ign. residue   ≤0.1% (as SO4)
refractive index   n20/D 1.499
density   1.20 g/mL at 20 °C(lit.)
storage temp.   2-8°C

Description

Biochem/physiol Actions

D-Panthenol is the alcohol analogue and biological precursor of D-pantothenic acid. These analogues are precursors in the biosynthesis of coenzyme A. D-Panthenol and D-Pantothenic acid are used in a variety of skin protection products. D-pantothenic acid may have a role in controlling keratinocyte proliferation and differentiation. D-Panthenol may be used for studies of skin protection emulsions from UV irradiation and as a humectant.

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Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
1

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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