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79972 Sigma

7-(Isobutoxycarbonyloxy)-3H-phenoxazin-3-one

suitable for fluorescence, ≥97.0% (HPLC)

Synonym: O7-(Isobutyloxycarbonyl)resorufin

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Properties

Related Categories Alphabetical, Biochemicals and Reagents, Fluorescent Enzyme Substrates, Fluorescent Probes, Labels, Particles and Stains
InChI Key   RVDFSVVDUVHHKE-UHFFFAOYSA-N
assay   ≥97.0% (HPLC)
fluorescence   λex 500 nm; λem ~593 nm in 0.1 M Tris pH 8.0 (after cleavage by esterase)
suitability   suitable for fluorescence

Description

Other Notes

Fluorogenic indicator for cell viability, cell permeant, ~2-times higher sensitivity than calcein-AM; additionally, 80-90 nm more long-wave shift of spectra. Shows esterase activity

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

Sensor Dyes

In 1998 R.F. Furchgott, L.J. Ignarro, and F. Murad received the Nobel Prize in Physiology and Medicine for their discoveries concerning nitric oxide as a signaling molecule in the cardiovascular syst...
Monika Baeumle
BioFiles 2011, 6.3, 23.
Keywords: Applications, Biochemistry, Biological processes, Cancer, Cardiovascular, Central Nervous System, Diseases, Extinction coefficient, Indicators, Inflammation, Methods, Microscopy, Neurotransmission, Sol-gel, Type

Peer-Reviewed Papers
15

References

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