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81333 Sigma

Poly-L-lysine hydrobromide

mol wt 20,000-30,000

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Properties

Related Categories Amino Acids, Biochemicals and Reagents, Homopolymers, Polyamino Acids
form   fibers
mol wt   mol wt 20,000-30,000
storage temp.   −20°C

Description

Components

Poly-L-lysine is a positively charged amino acid polymer with approximately one HBr per lysine residue. The hydrobromide allows the poly-L-lysine to be in a crystalline form soluble in water. A small amount of product may be found in the beta structure because the HBr interferes with hydrogen bonding between amino and either the carboxyl groups or N or O containing moieties.

Caution

Sterile solutions are stable for up to 2 years when stored at 2-8°C. It should be stored desiccated at -20°C.

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Biochem/physiol Actions

Poly-L-lysine hydrobromide is used in the construction of biocompatible nanocapsules and for positively charged NH2 group modification of bioactive surfaces in applications such as microarray and micropattern assembly.

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles

Articles

Poly(Amino Acid) Block Copolymers for Drug Delivery and other Biomedical Applications

Carmen Scholz Department of Chemistry, University of Alabama in Huntsville Huntsville, AL 35899 Email: scholzc@uah.edu
Keywords: Addition reactions, Asymmetric synthesis, Building blocks, Catalysis, Degradations, Living polymerization, PEGylations, Polymerization reactions, Precipitation, Proteomics, Ring-opening polymerization, Solvents

Peer-Reviewed Papers
15

References

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