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86339 Sigma

Sodium taurocholate hydrate

≥97.0% (TLC)

Synonym: Taurocholic acid sodium salt

  • CAS Number 345909-26-4

  • Empirical Formula (Hill Notation) C26H44NNaO7S · xH2O

  • Molecular Weight 537.68 (anhydrous basis)

  •  Beilstein Registry Number 3901620

  •  EC Number 205-653-7

  •  MDL number MFCD00150819

  •  PubChem Substance ID 57653098

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Properties

Related Categories Anionic Detergents, Bile Salts, Bile acids and Derivatives, Biochemicals and Reagents, Cell Culture,
description   anionic
InChI Key   RDAJAQDLEFHVNR-NEMAEHQESA-M
assay   ≥97.0% (TLC)
optical activity   [α]20/D +23±1°, c = 3% in H2O (dry matter)
impurities   ≤1% taurine
  ≤2% cholic acid
solubility   H2O: 50 mg/mL clear

Description

Other Notes

For the solubilization of unconjugated bilirubin

Preparation Note

Sodium taurocholate hydrate yields a clear, colorless solution in water at 50 mg/ml.

Application

Sodium taurocholate hydrate was used as an emulsifier in in situ preparation of digestive enzymes.

Biochem/physiol Actions

Taurocholic acid is the main end product of cholesterol catabolism. During enterohepatic circulation, bile taurocholic acid is converted by the microorganisms to taurodeoxycholic acid and deoxycholic acid. These are reabsorbed by the liver via a carrier-mediated process and converted by liver enzymes to taurocholic acid.

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Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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