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89270 Sigma

Thymidine

≥99.0% (HPLC)

Synonym: 1-(2-Deoxy-β-D-ribofuranosyl)-5-methyluracil, 1-(2-Deoxy-β-D-ribofuranosyl)thymine, 2′-Deoxythymidine, Thymine deoxyriboside, dT

  • CAS Number 50-89-5

  • Empirical Formula (Hill Notation) C10H14N2O5

  • Molecular Weight 242.23

  •  Beilstein Registry Number 89285

  •  EC Number 200-070-4

  •  MDL number MFCD00006537

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Properties

Related Categories Biochemicals and Reagents, Nucleosides, Nucleosides, Nucleotides, Oligonucleotides More...
InChI Key   IQFYYKKMVGJFEH-XLPZGREQSA-N
assay   ≥99.0% (HPLC)
optical activity   [α]20/D +19±1°, c = 1% in H2O
mp   186-188 °C(lit.)
  186-188 °C

Description

Application

Thymidine (dT) is a pyrimidine deoxyriboside (deoxynucleoside) that upon sequential phosphorylation to deoxythymidine triphospate (dTTP) is used to synthesize DNA and the T-loop of transfer RNA. Thymidine is as substrate of Thymidine kinase EC 2.7.1.21 which phosphorylates the nucleoside with a phosphate derived from ATP. dT may be used to study the distribution, specificity and kinetics of a family of thymidine kinase(s).

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
XP2071000
Protocols & Articles
Peer-Reviewed Papers
15

References

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