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90190 Sigma

Transferrin from human blood plasma

≥95% (GE)

Synonym: Human transferrin, Siderophilin

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Properties

Related Categories Biochemicals and Reagents, Plasma & Blood Proteins, Plasma, Blood, and Related Proteins and Reagents, Proteins and Derivatives, Transferrin More...
assay   ≥95% (GE)
mol wt   Mr ~79550
impurities   ≤0.01% iron traces (AAS)
solubility   H2O: soluble50 mg/mL, clear, colorless to faintly yellow or pink
storage temp.   2-8°C
Gene Information   human ... TF(7018)

Description

Application

Transferrin is an important supplement in serum-free tissue culture media.

Other Notes

Review: Iron transport and storage

Biochem/physiol Actions

Transferrin is glycoprotein, approx. 80 kDa, with two binding sites for iron. It transports iron from its primary store in the liver to tissues that require iron, primarily bone marrow and spleen, but also brain. It binds Fe3+ extremely tightly (Kdiss 10-30 to 10-27), protecting against oxidant effects of free plasma iron.

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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