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93829 Sigma

L-Tyrosine

BioUltra, ≥99.0% (NT)

Synonym: (S)-2-Amino-3-(4-hydroxyphenyl)propionic acid, 3-(4-Hydroxyphenyl)-L-alanine

  • CAS Number 60-18-4

  • Linear Formula 4-(HO)C6H4CH2CH(NH2)CO2H

  • Molecular Weight 181.19

  •  Beilstein Registry Number 392441

  •  EC Number 200-460-4

  •  MDL number MFCD00002606

  •  PubChem Substance ID 24889931

  •  eCl@ss 32160406

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Properties

Related Categories Amino Acids, Amino acids, BioUltra, Biochemicals and Reagents, Cell Biology,
InChI Key   OUYCCCASQSFEME-QMMMGPOBSA-N
product line   BioUltra
assay   ≥99.0% (NT)
optical activity   [α]20/D −11.5±1.0°, c = 4% in 1 M HCl
impurities   insoluble matter, passes filter test
  ≤0.5% foreign amino acids
ign. residue   ≤0.1%
loss   ≤0.2% loss on drying, 20 °C (HV)
mp   >300 °C (dec.)(lit.)
solubility   1 M HCl: soluble25 mg/mL, clear, colorless (hot)
anion traces   chloride (Cl-): ≤400 mg/kg
  sulfate (SO42-): ≤300 mg/kg
cation traces   Al: ≤5 mg/kg
  As: ≤0.1 mg/kg
  Ba: ≤5 mg/kg
  Bi: ≤5 mg/kg
  Ca: ≤10 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤5 mg/kg
  K: ≤50 mg/kg
  Li: ≤5 mg/kg
  Mg: ≤5 mg/kg
  Mn: ≤5 mg/kg
  Mo: ≤5 mg/kg
  NH4+: ≤200 mg/kg
  Na: ≤200 mg/kg
  Ni: ≤5 mg/kg
  Pb: ≤5 mg/kg
  Sr: ≤5 mg/kg
  Zn: ≤5 mg/kg
absorption   absorption0.5M/310 nm, 1 M HCl cut-off

Description

Other Notes

Amino acid precursor of dopamine and other catecholamines

Growth requirements of various microorganisms

Application

L-Tyrosine was used in tyrosine hydroxylase (TH) enzyme activity assay. It was also used as a substrate for tyrosinase enzyme in the growth media of Vibrio cholerae strains to stimulate melanin formation. It may be used as a precursor in the synthesis of (-)-MY 336a. MY 336a, a β-adrenergic receptor antagonist, was initially isolated from the culture broth of Streptomyces gabonae KY2234 (ATCC 15282). It may be used in the synthesis of 3-bromo-L-tyrosine and 3,5-dibromo-L-tyrosine.

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.




All labs need water
Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
YP2275600

Documents

Certificate of Analysis

Protocols & Articles

Articles

Characteristic Metabolites for Inborn Errors of Amino Acid Metabolism

Inborn errors of metabolism are caused by changes in specific enzymatic reactions and hundreds of different such alterations, which affect about 1 of every 5000 newborns, have been characterized. The...
Keywords: Indicators, Metabolism, Metabolites

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Related Content

Amino Acids Reference Chart

The hydrophobicity index is a measure of the relative hydrophobicity, or how soluble an amino acid is in water. In a protein, hydrophobic amino acids are likely to be found in the interior, whereas h...

Peer-Reviewed Papers
15

References

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