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95144 Sigma

Retinol

BioXtra, ≥97.5% (HPLC), ~3100 U/mg

Synonym: Axerophthol, Vitamin A alcohol, Vitamin A, Vitamin A1, all-trans-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol

  • CAS Number 68-26-8

  • Empirical Formula (Hill Notation) C20H30O

  • Molecular Weight 286.45

  •  Beilstein Registry Number 403040

  •  EC Number 200-683-7

  •  MDL number MFCD00001552

  •  PubChem Substance ID 57653654

  •  eCl@ss 34058018

  • Popular Documents:  Datasheet (PDF)  

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Properties

Related Categories Biochemicals and Reagents, Carotenoid, Cell Biology, Isoprenoids, Lipids,
InChI Key   FPIPGXGPPPQFEQ-OVSJKPMPSA-N
product line   BioXtra
assay   ≥97.5% (HPLC)
shelf life   limited shelf life
mp   56-61 °C
  61-63 °C(lit.)
shipped in   dry ice
storage temp.   −20°C

Description

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Unit Definition

1 U corresponds to 1 international U acc. to Ph Eur II, 217 (1983)

Biochem/physiol Actions

Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain.
Retinol is biological active in a wide range of processes.

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Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
VH6750000
Protocols & Articles

Articles

MRT One Step Retinol Synthesis

Benefit from MRT & Flow Chemistry: 70% improvement in yield by protecting the extremely sensitive product.
Matthias Junkers
Aldrich ChemFiles 2009, 9.4, 10.
Keywords: Chemfiles, Continuous flow chemistry, Degradations, Microreactor technology

Retinoic Acid and Gene Expression

All-trans retinoic acid (RA, ATRA) is a pleiotropic activation factor that regulates genes associated with normal vertebrate cellular processes such as cell differentiation, cell proliferation, apopt...
BioFiles 2008, 3.9, 12.
Keywords: Apoptosis, Cancer, Cell proliferation, Cellular processes, Chromatin immunoprecipitation, Condensations, Degradations, Diseases, Gene expression, Hormones, Immunoprecipitation, Ligands, Metabolism, Oxidations, Phosphorylations, Polymerase chain reaction, Sequences, Teratogens, Transcription, Type, Ubiquitinations, Usage, Vitamins

Peer-Reviewed Papers
15

References

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92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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