|Related Categories||Biochemicals and Reagents, Coatings, Excipients for R&D Use Only More...|
|assay||25.0-30.0% (saponification value * 0.1534)|
|28.5-31.5% solids basis|
|impurities||≤0.5% sulfated ash(verified on random samples only)|
|≤0.500% particulate matter, agglomerates|
|≤100 ppm residual monomer vinyl acetate|
|≤15000 ppm acetic acid|
|≤20 ppm heavy metals(verified on random samples only)|
|≤4.0% povidone(N content/0.126)|
|viscosity||≤100 mPa.s(20 °C, Brookfield RVT)(SP. 1, 100 PRM)|
appearance and solubility of a film must conform
Kollicoat SR is use in the pharmaceutical industry as a controlled-release coating on pellets or as a matrix in tablets. Kollicoat polymers can be employed as film coatings (intelligent surfaces) with controlled-release agents, for instant-release, enteric or sustained-release applications. Kollicoat polymers can be used with all standard coating equipment and are cost-effective, delivering maximum quality in terms of function, stability, and appearance.
Kollicoat is a registered trademark of BASF SE
Compressibility of floating pellets with verapamil hydrochloride coated with dispersion Kollicoat SR 30 D. Sawicki W, Lunio R. Eur. J. Pharm. Biopharm. 60, 153-158, (2005)
New insights on poly(vinyl acetate)-based coated floating tablets: characterisation of hydration and CO2 generation by benchtop MRI and its relation to drug release and floating strength. Strübing S, Abboud T, Contri RV, et al. Eur. J. Pharm. Biopharm. 69, 708-717, (2008)
Sustained-release of buspirone HCl by co spray-drying with aqueous polymeric dispersions. Al-Zoubi N, Alkhatib HS, Bustanji Y, et al. Eur. J. Pharm. Biopharm. 69, 735-742, (2008)
Prediction of dissolution time and coating thickness of sustained release formulations using Raman spectroscopy and terahertz pulsed imaging. Müller J, Brock D, Knop K, et al. Eur. J. Pharm. Biopharm. 80, 690-697, (2012)
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