A1625 Sigma

Acetoacetyl coenzyme A sodium salt hydrate

cofactor for acyl transfer

DOWNLOAD MSDS (PDF)

Synonym: Acetoacetyl-CoANa3

  • CAS Number 1420-36-6 (free acid)

  • Empirical Formula (Hill Notation) C25H40N7O18P3S · xNa+ · yH2O

  • Molecular Weight 851.61 (anhydrous free acid basis)

  •  PubChem Substance ID 24890567

Description

Application

Substrate for acetoacetyl-CoA thiolase EC 2.3.1.9; Role in the biosynthesis of nonactin.

Acetoacetyl coenzyme A (Acetoacetyl-CoA) may be used as a substrate for a number of enzymes including; acetoacetyl-CoA thiolase (EC 2.3.1) which produces acetyl-CoA in reverse condensation reaction and (3-Hydroxy-3-methylglutaryl coenzyme A (CoA) synthase (HMGCS)) which produces 3-hydroxy-3-methylglutaryl (HMG)-CoA in the mevalonate pathway leading to terpenoid biosynthesis. Acetoacetyl-CoA is also a precursor of poly-beta-hydroxybutyrate polymers in microorganisms.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. A1625.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

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