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  • A4562 - 5-(N,N-Dimethyl)amiloride hydrochloride

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A4562 Sigma

5-(N,N-Dimethyl)amiloride hydrochloride

DOWNLOAD MSDS (PDF)

Synonym: 3-Amino-N-(aminoiminoethyl)-5-(dimethylamino)-6-chloropyrazinecarboxamide hydrochloride, DMA

5-(N,N-Dimethyl)amiloride hydrochloride
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Properties

Related Categories Amiloride and Derivatives, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, DIG-DY,
storage temp.   2-8°C
Gene Information   human ... SCNN1A(6337), SCNN1B(6338), SCNN1D(6339), SCNN1G(6340), SLC9A1(6548)
mouse ... Scnn1a(20276), Scnn1b(20277), Scnn1d(140501), Scnn1g(20278)
rat ... Scnn1a(25122), Scnn1b(24767), Scnn1g(24768), Slc9a1(24782), Slc9a2(24783), Slc9a3(24784)

Description

Biochem/physiol Actions

Selective blocker of Na+/H+ antiport; IC50 = 6.9 μM.

Application

5-(N,N-Dimethyl)amiloride hydrochloride is a selective blocker of Na2/H+ antiport. 5-(N,N-Dimethyl)amiloride hydrochloride has been investigated for its ability to reduce inflammatory pain.

Price and Availability

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