6-Thioguanine
Hybri-Max™, 50 ×, γ-irradiated, lyophilized powder, BioXtra, suitable for hybridoma
DOWNLOAD MSDS (PDF)Synonym:
2-
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CAS Number 154-42-7
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Empirical Formula (Hill Notation) C5H5N5S
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Molecular Weight 167.19
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Beilstein Registry Number 157765
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EC Number 205-827-2
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MDL number MFCD00233553
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PubChem Substance ID 24890892
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Popular Documents: Product Information Sheet (PDF) | Specification Sheet (PDF) | RAMAN FTIR (PDF)
Properties
| Related Categories | Cell Culture, Conditioned Media, Media Supplements and Reagents, Hybridoma Platform, Hybridoma Reagents, Reagents and Supplements, |
| grade | Hybri-Max™ |
| sterility | γ-irradiated |
| product line | BioXtra |
| assay | ~98% |
| form | lyophilized powder |
| concentration | 50 × |
| impurities | endotoxin, tested |
Description
Application
Used in hybridoma formation applications as a selection agent.
Reconstitution
Reconstitute contents of vial with 10 ml sterile cell culture medium. Stock solution is sufficient to prepare 500 ml medium. Final working concentration: 30 μM 2-amino-6-mercaptopurine.
Biochem/physiol Actions
Ribosylated and phosphorylated by the same pathway as natural purine bases; as the nucleotide, inhibits a variety of cellular processes involved in nucleic acid synthesis. Has a long history as an effective treatment of leukemia.1
Legal Information
Hybri-Max is a trademark of Sigma-Aldrich Co. LLC
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γ-irradiated, lyophilized powder, BioXtra, suitable for hybridoma
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