A9605 Sigma

AC-93253 iodide

≥98% (HPLC)

DOWNLOAD MSDS (PDF)

Synonym: 2-[3-(1,3-Dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)-1-propenyl]-3-ethyl-benzothiazolium iodide

Properties

Related Categories A-AM, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Gene Regulation and Expression,
assay   ≥98% (HPLC)
form   solid
storage condition   desiccated
color   dark purple
solubility   DMSO: >10 mg/mL
  H2O: insoluble
storage temp.   2-8°C

Description

Biochem/physiol Actions

AC-93253 is a potent, cell permeable, subtype selective RAR (RARα) agonist. EC50 = 6.3 μM. AC-93253 has high selectivity; 89% for RARα vs 67% for RARβ1, 35% for RARβ2, and 11% for RARγ.

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