BAD from mouse ≥70% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution

Properties

Related Categories	Apoptosis and Cell Cycle, Bcl-2 Family Proteins, Bcl-2 Family Proteins and Antibodies, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Enzyme Substrates, Enzymes, Inhibitors, and Substrates, Peptides and Proteins, Peptides for Cell Biology, Protein Kinase B, Protein Kinase Related Peptides, Protein Kinase Substrates, Substrates by Enzyme More...
recombinant	expressed in E. coli
description	full-length murine Bad with an N-terminal histidine-tag.
assay	≥70% (SDS-PAGE)
form	buffered aqueous glycerol solution
mol wt	mol wt 31 kDa
storage temp.	−20°C
Gene Information	mouse ... Bad(12015)

Description

Physical form

Supplied as a solution in phosphate buffered saline containing 250 mM imidizole and 50% glycerol.

Biochem/physiol Actions

Bad, a pro-apoptotic factor, is a member of the Bcl-2 family. Cytokine-induced phosphorylation of Bad results in it being sequested in the cytosol. In the absence of cytokines such as interleukin 3 (IL-3), Bad dephosphorylation occurs, causing the release of cytochrome c from the mitochondria.