|Related Categories||Allium cepa (Onion), Biochemicals and Reagents, Lipids, Metabolic Pathways, Metabolomics,|
|biological source||from semisynthetic|
Brassicasterol is a phytosterol found in rapeseed and canola oils; it is also present in marine algae and shellfish. Brassicasterol has been shown to inhibit sterol Δ24-reductase, an enzyme involved in the mammalian cholesterol biosynthesis pathway.1
The amount of cholesterol that is synthesized in the liver is tightly regulated by dietary cholesterol levels. When dietary intake of cholesterol is high, synthesis is decreased and when dietary inta...
BioFiles 2007, 2.7, 6.
Keywords: Gene expression, Transcription
Cloning, mechanistic and functional analysis of a fungal sterol C24-methyltransferase implicated in brassicasterol biosynthesis. Pereira M, Song Z, Santos-Silva LK, et al. Biochim. Biophys. Acta 1801, 1163-1174, (2010)
The search of new biomarkers to identify Alzheimer's disease: an editorial comment to T. Vanmierlo et al. 'The plant sterol brassicasterol and additional CFS biomarker in Alzheimer's Disease' (1). Lobo A, Quintanilla MA. Acta Psychiatr. Scand. 124, 163-164, (2011)
Plants steroid hormones, brassinosteroids: current highlights of molecular aspects on their synthesis/metabolism, transport, perception and response. Bishop, G.J., and Yokota, T. Plant Cell Physiol. 42, 114-20, (2001)
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