|Related Categories||Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors,|
|solubility||ethanol: soluble10 mg/mL|
|Gene Information||human ... SLC2A1(6513), SLC2A4(6517)|
Inhibits natural killer (NK) cell activity in a dose-dependent manner without affecting target cell binding. Shown to inhibit insulin-induced translocation of both GLUT4 and GLUT1 in a dose-dependent manner. Also reported to inhibit agonist-induced Ca2+ entry into endothelial cells and catecholamine secretion in intact and permeabilized chromaffin cells.
Certificate of Analysis
Certificate of Origin
The Warburg effect is the enhanced conversion of glucose to lactate observed in tumor cells, even in the presence of normal levels of oxygen. Otto Heinrich Warburg demonstrated in 1924 that cancer ce...
Keywords: Aerobic, Cancer, Cell proliferation, Clinical, Glycolysis, PAGE, Phosphorylations, Transcription
Glucose metabolism is regulated by the opposing actions of insulin and glucagon. Insulin is released from pancreatic ß cells in response to high blood glucose levels and regulates glucose metabolism ...
Linda Stephenson, Ph.D.
Biofiles v6 n4, 2011
Keywords: Apoptosis, Biological processes, Carboxylations, Diabetes, Gene expression, Gluconeogenesis, Glycolysis, Hormones, Metabolism, Metabolites, Transcription, Transduction
Roles of inhibitors of myosin light chain kinase and tyrosine kinase on cation influx in agonist-stimulated endothelial cells. Takahashi, R., et al. Biochem. Biophys. Res. Commun. 235, 657-662, (1997)
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