|Related Categories||AMPA/Kainate Antagonists, Bioactive Small Molecules, CI-CY, Cell Biology, Cell Signaling and Neuroscience,|
|storage condition||protect from light|
|solubility||DMSO: >10 mg/mL|
|Gene Information||rat ... Gria1(50592), Grik1(29559), Grik2(54257), Grik4(24406), Grin2a(24409)|
Potent, competitive AMPA/kainate glutamate receptor antagonist.
Effect of 6-cyano-23-dihydroxy-7-nitro-quinoxaline (CNQX) on dorsal root- NMDA- kainate- and quisqualate-mediated depolarization of rat motoneurones in vitro. Long, et al. Br. J. Pharmacol. 100, 850-854, (1990)
Differential effects of the excitatory amino acid antagonists, 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) and 3-((±)-2-carboxypiperazin-4-yl)propyl-1-phosphonic acid (CPP), on spinal reflex activity in mice. Turski, et al. Neurosci. Lett. 113, 66, (1990)
Electrophysiological characterization of spino-sciatic and cortico-sciatic associative plasticity: modulation by trans-spinal direct current and effects on recovery after spinal cord injury in mice. Ahmed Z J. Neurosci. 33(11), 4935-46, (2013)
Cross-sensitization between cocaine and acute restraint stress is associated with sensitized dopamine but not glutamate release in the nucleus accumbens. Garcia-Keller C, Martinez SA, Esparza MA, et al. Eur. J. Neurosci. 37(6), 982-95, (2013)
Autism-associated mutations in ProSAP2/Shank3 impair synaptic transmission and neurexin-neuroligin-mediated transsynaptic signaling. Arons MH, Thynne CJ, Grabrucker AM, et al. J. Neurosci. 32(43), 14966-78, (2012)
The postsubiculum and spatial learning: the role of postsubicular synaptic activity and synaptic plasticity in hippocampal place cell, object, and object-location memory. Bett D, Stevenson CH, Shires KL, et al. J. Neurosci. 33(16), 6928-43, (2013)
Presynaptic α4β2 nicotinic acetylcholine receptors increase glutamate release and serotonin neuron excitability in the dorsal raphe nucleus. Garduño J, Galindo-Charles L, Jiménez-Rodríguez J, et al. J. Neurosci. 32(43), 15148-57, (2012)
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