CD4 monoclonal antibody | Flow Cytometry | C1805

Properties

Related Categories	Alphabetical Index, Analytical Cytology, Antibodies, Antibodies for Cell Biology, Antibodies for Immune Cell Signaling and Blood, Antibodies to Human Leukocytes, CD0-CDC, Clone Index, Primary Antibodies, Q-R More...
species reactivity	human
application(s)	flow cytometry: 5 μL using 1 × 10⁶ cells
clone	Q4120, monoclonal
antibody form	purified immunoglobulin
form	buffered aqueous solution
isotype	IgG1
mol wt	antigen mol wt 59 kDa
shipped in	wet ice
storage temp.	2-8°C
Gene Information	human ... CD4(920)

Description

Immunogen

CD4-transfected mouse T-cell hybridoma, 3DT, followed by CD4+ human T-cell CEM cells.

Antigen Background

CD4 is a single chain transmembraneous glycoprotein from the immunoglobulin superfamily. It is expressed on the helper/inducer T subset, on most medullary thymocytes, on microglial, dendritic and on some malignancies of T cell origin. The antigen binds to MHC class II molecules and is associated with p56^lck protein tyrosine kinase.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

Specificity

Recognizes the CD4. The epitope recognized by the Q4120 clone is located on 1-183 aa and is sensitive to formalin fixation and paraffin embedding. 5th Workshop: code no. CD04.11

Price and Availability

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