Caspase 8 (SK-16) antibody | Western | C3101

Properties

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species reactivity	human
application(s)	microarray: suitable
	western blot: 1:1,000 using human Burkitt lymphoma Raji cell extract
clone	polyclonal
antibody form	IgG fraction of antiserum
form	buffered aqueous solution
shipped in	dry ice
storage temp.	−20°C
Gene Information	human ... CASP8(841)

Description

Immunogen

synthetic peptide corresponding to amino acids 209-224 of the human caspase 8a/MACHα1 precursor, conjugated to KLH. The sequence contains the N-terminal region of the enzyme p18 subunit and is identical in other human caspase 8 isoforms (caspase 8b/MACHα2, MACHβ3, MACHβ4) and highly conserved (>85%) in mouse caspase 8.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Specificity

By immunoblotting, the antibody reacts with caspase 8a (55 kDa) and caspase 8b (54 kDa) and weakly cross-reacts with MACHβ3/MACHβ4 isoforms (30-32 kDa).

Price and Availability

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