Cytochrome P450 Microsome Preparation human
3A4 Isozyme, recombinant, expressed in Saccharomyces cerevisiae, coexpressed with human NADPD reductase and human cytochrome b5
DOWNLOAD MSDS (PDF)Synonym: Cerosomes
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Properties
| Related Categories | Application Index, Biochemicals and Reagents, Cell Signaling Enzymes, Cerosomes Cytochrome P450 (CYP) Active Microsome Preparations, Cytochrome P450s (CYPs), |
| recombinant | expressed in Saccharomyces cerevisiae |
| activity | 1.5-2.0 units/pmol enzyme |
| secondary activity | 1300-1700 units/mg protein (Reductase activity) |
| shipped in | dry ice |
| storage temp. | −70°C |
Description
Analysis Note
CYP450 content: 40.0-60.0 picomoles per mg protein
Other Notes
For more more information visit our drug metabolism resources for Cytochrome P450 microsome preparations.
Unit Definition
P450 Activity: One unit will oxidize 1.0 picomole of 7-benzoxymethyloxy-3-cyan
Reductase Activity: One unit will reduce 1 nanomole of cytochrome c per minute in the presence of NADPH at pH 7.8 at 25 °C.
Physical form
Supplied as a solution containing 50 mM potassium phosphate, pH 7.4, 5% glycerol, 1 mM EDTA, 1 mM PMSF, and 2 mM DTT
Price and Availability
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