|Related Categories||Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Protein Degradation, Antibodies to Proteolysis/Proteases,|
|species reactivity||human, rat, mouse|
|application(s)||western blot: 1:1,000|
|antibody form||affinity isolated antibody|
|form||buffered aqueous glycerol solution|
|shipped in||wet ice|
human ... CAPN2(824)|
mouse ... Capn2(12334)
rat ... Capn2(29154)
synthetic peptide corresponding to the large subunit of human calpain II (m-calpain, Clpn02, calpain-2).
Calpains are calcium-dependent cysteine proteases that are expressed ubiquitously in eukaryotes. Calpains regulate diverse cellular processes such as development, apoptosis and signal transduction 1,2. Calpain-2 has been implicated in the development of synaptic plasticity and cataract 3,4. Anti-Calpain-2 is specific for the large subunit of calpain-2 in humans, mice and rats. The antibody does not bind to other members of the calpain protein family.
Solution in phosphate buffered saline containing 50% glycerol, 1% bovine serum albumin, and 0.02% sodium azide.
Anti-Calpain-2, Large Subunit antibody is suitable for use in western blot (1:1000) and immunoblot (80kDa and 58kDa).
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Keywords: Buffers, Cell biology, Epigenetics, Immunohistochemistry, Immunoprecipitation, Molecular biology, Neuroscience, Western blot
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