Calpain-2, Large Subunit antibody | Western | C3989

Properties

Related Categories	Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Protein Degradation, Antibodies to Proteolysis/Proteases, CA1-CAL, Primary Antibodies More...
species reactivity	human, rat, mouse
application(s)	western blot: 1:1,000
clone	polyclonal
concentration	1 mg/mL
antibody form	affinity isolated antibody
form	buffered aqueous glycerol solution
shipped in	wet ice
storage temp.	−20°C
Gene Information	human ... CAPN2(824) mouse ... Capn2(12334) rat ... Capn2(29154)

Description

Immunogen

synthetic peptide corresponding to the large subunit of human calpain II (m-calpain, Clpn02, calpain-2).

General description

Calpains are calcium-dependent cysteine proteases that are expressed ubiquitously in eukaryotes. Calpains regulate diverse cellular processes such as development, apoptosis and signal transduction ^1,². Calpain-2 has been implicated in the development of synaptic plasticity and cataract ^3,⁴. Anti-Calpain-2 is specific for the large subunit of calpain-2 in humans, mice and rats. The antibody does not bind to other members of the calpain protein family.

Physical form

Solution in phosphate buffered saline containing 50% glycerol, 1% bovine serum albumin, and 0.02% sodium azide.

Application

Anti-Calpain-2, Large Subunit antibody is suitable for use in western blot (1:1000) and immunoblot (80kDa and 58kDa).

Price and Availability

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