|Related Categories||Application Index, Biochemicals and Reagents, Cancer Research, Cell Biology, Cell Signaling Enzymes,|
|recombinant||expressed in baculovirus infected insect cells (BTI-TN-5B1-4)|
|packaging||vial of 0.5 nmol|
|Gene Information||human ... CYP4F2(8529)|
Cytochrome P450 is a heterogeneous family of isozymes whose primary function is to oxidize small molecules, both as a function of intermediary metabolism (e.g., fatty acids) and to detoxify exogenous compounds (drugs or toxins). Some isoforms have narrow substrate specificity, while others are promiscuous.1
The CYP4F2 isoform catalyzes the 20-hydroxylation of leukotriene B4.
Solution in 100 mM potassium phosphate buffer, pH 7.4.
Expression of the CYP4F3 gene. tissue-specific splicing and alternative promoters generate high and low K(m) forms of leukotriene B(4) omega-hydroxylase. Christmas, P., et al. J. Biol. Chem. 274, 21191, (1999)
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