|Related Categories||Alphabetical Index, Analytical Cytology, Antibodies, Antibodies for Cell Biology, Antibodies for Immune Cell Signaling and Blood,|
|application(s)||flow cytometry: 10 μL using 1 × 106 cells|
|antibody form||purified immunoglobulin|
|form||buffered aqueous solution|
|mol wt||antigen mol wt 180 kDa|
|shipped in||wet ice|
|Gene Information||human ... PTPRC(5788)|
influenza virus activated CA1 T-cell line.
CD45RO is a single-chain transmembranous glycoprotein, which represents the low molecular weight isoform of the leukocyte common antigen (LCA). It is expressed on most thymocytes, about 45% of resting peripheral blood T cells, virtually all T cells in skin reactive infiltrates and the majority of T cell malignancies. It is also found on a subset of B cells and on some B cell lymphomas. NK-cells do not express this antigen.
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.
Recognizes the CD45RO human cell surface glycoprotein. The epitope recognized by this antibody is sensitive to neuraminidase digestion, but not to formalin fixation and paraffin embedding. The antibody is capable of detecting CD45RO antigen in tissue sections processed with a variety of fixatives. The antibody also detects CD45RO antigen in frozen sections, cell suspension, smears, imprints and cytospins.
4th Workshop: code no. N31
5th Workshop: code no. T081, CD45.43
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Keywords: Buffers, Cell biology, Epigenetics, Immunohistochemistry, Immunoprecipitation, Molecular biology, Neuroscience, Western blot
Terry, L.A., et al. J. Clin. Pathol. 64, 331, (1988)
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