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Articles
Cholesterol Biosynthesis
Cholesterol levels in the body come from two sources, dietary intake and biosynthesis. The majority of cholesterol utilized by healthy adults is synthesized in the liver, which produces ~70% of the t...
BioFiles 2007, 2.7, 3.
Keywords: Catalysis, Decarboxylations, Metabolic Pathways, Oxidations, PAGE, Phosphorylations, Reductions
Protocols
Enzymatic Assay of Cholesterol Oxidase
1. OBJECTIVE To standardize a procedure for the determination of the enzymatic assay of Cholesterol Oxidase.
Keywords: Enzyme activity, Extinction coefficient, Isomerizations
Papers
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A Novel Non-toxic Combined CTA1-DD And ISCOMS Adjuvant Vector For Effective Mucosal Immunization Against Influenza Virus. Eliasson, D.G., et al. Vaccine 29, 3951-61, (2011)
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Optimized lentiviral transduction of mouse bone marrow-derived mesenchymal stem cells. David M. Ricks et al Stem Cells Dev. 17, 441-50, (2008)
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Determination of tie-line fields for coexisting lipid phases: an ESR study. Andrew K Smith et al J. Phys. Chem. B 113, 3957-71, (2009)
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Structure-activity relationships in cholapod anion carriers: enhanced transmembrane chloride transport through substituent tuning. Beth A. McNally et al Chemistry 14, 9599-606, (2010)
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Functional promoter polymorphisms govern differential expression of HMG-CoA reductase gene in mouse models of essential hypertension. Parshuram J. Sonawane et al PLoS ONE 6, e16661, (2011)
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Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals. Markus A Lill et al J. Med. Chem. 48, 5666-74, (2005)
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Elevated levels of oxidized cholesterol metabolites in Lewy body disease brains accelerate alpha-synuclein fibrilization. Daryl A Bosco et al Nat. Chem. Biol. 2, 249-53, (2006)
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Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors. Sean Ekins et al Drug Metab. Dispos. 35, 493-500, (2007)
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Synthesis and in vitro biological evaluation of ring B abeo-sterols as novel inhibitors of Mycobacterium tuberculosis. Xiaomei Wei et al Bioorg. Med. Chem. Lett. 18, 5448-50, (2008)
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Synthesis, characterization and in vitro antibacterial activity of new steroidal 5-en-3-oxazolo and thiazoloquinoxaline. Salman A Khan et al Eur. J. Med. Chem. 43, 2040-4, (2008)
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Synthesis, structure elucidation and antibacterial evaluation of new steroidal -5-en-7-thiazoloquinoxaline derivatives. Salman Ahmad Khan et al Eur. J. Med. Chem. 43, 2257-61, (2008)
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Synthesis, characterization and in vitro antibacterial activity of thiourea and urea derivatives of steroids. Salman Ahmad Khan et al Eur. J. Med. Chem. 43, 2272-7, (2008)
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Efficient chemoenzymatic synthesis, cytotoxic evaluation, and SAR of epoxysterols. João F S Carvalho et al J. Med. Chem. 52, 4007-19, (2009)
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Synthesis of new alkylaminooxysterols with potent cell differentiating activities: identification of leads for the treatment of cancer and neurodegenerative diseases. Philippe de Medina et al J. Med. Chem. 52, 7765-77, (2009)
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Bioactive scalaranes from the Thai sponge Hyrtios gumminae. Chulabhorn Mahidol et al J. Nat. Prod. 72, 1870-4, (2009)
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An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds. Yunbao Liu et al J. Nat. Prod. 73, 1193-5, (2010)
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Cytotoxic and PPARs transcriptional activities of sterols from the Vietnamese soft coral Lobophytum laevigatum. Tran Hong Quang et al Bioorg. Med. Chem. Lett. 21, 2845-9, (2011)
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Fuscoside E: a strong anti-inflammatory diterpene from Caribbean octocoral Eunicea fusca. Eduardo Reina et al Bioorg. Med. Chem. Lett. 21, 5888-91, (2011)
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Merck 14,2201
Beil. 6,IV,4000 / Beil. 6,III,2607
Fieser 1,141
FT-IR 1 (2), 1048:B / FT-IR 2 (3), 4220:D / FT-NMR 1 (3), 568:A / IR-Spectra (2), 1048:B / IR-Spectra (2), 1277:H / IR-Spectra (3), 1493:H / NMR-Reference 2 (2), 919:B / RegBook 1 (2), 2855:G / Sax 6, 787 / Sigma FT-IR 1 (1), 1207:D / Structure Index 1, 457:B:5