Synonym: (+)-Vitamin D3, 7-Dehydrocholesterol activated, Activated 7-dehydrocholesterol, Calciol
|Related Categories||Antitumor Agents, Bioactive Small Molecules, C-CH, Cancer Research, Cell Biology,|
1, 5 g in glass bottle
Vitamin D acts through a receptor that is a member of the ligand-dependent transcription factor superfamily. Modulates the proliferation and differentiation of both normal and cancer cells. Has antiproliferative and antimetastatic effects on breast, colon, and prostate cancer cells. Activated vitamin D receptors in intestine and bone maintain calcium absorbance and homeostasis.
Certificate of Analysis
Certificate of Origin
|Precautionary statements||P260-P280-P284-P301 + P310-P310|
|Personal Protective Equipment||Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges|
|Hazard Codes (Europe)||T+|
|Risk Statements (Europe)||24/25-26-48/25|
|Safety Statements (Europe)||28-36/37-45|
|RIDADR||UN 2811 6.1 / PGII|
Vitamin D2 (ergocalciferol) is naturally synthesized from ergosterol by invertebrates, fungi, and plants in response to ultraviolet B irradiation, while vitamin D3 synthesis (cholecalciferol) is uniq...
BioFiles 2009, 4.6, 4.
Keywords: Absorption, Angiogenesis, Biological processes, Cancer, Clinical, Gene expression, Growth factors, Hormones, Hydroxylations, Ligands, Metabolites, Transcription, Vitamins
Effect of cholecalciferol and levo carnitine on plasma glucose, plasma insulin and insulin resistance in type 2 diabetic rats. Anwar MK, Hussain MM, Khan MA, et al. J. Pak. Med. Assoc. 63(3), 374-9, (2013)
Effect of calcium plus vitamin D supplementation during pregnancy in Brazilian adolescent mothers: a randomized, placebo-controlled trial. Diogenes ME, Bezerra FF, Rezende EP, et al. Am. J. Clin. Nutr. 98(1), 82-91, (2013)
High vitamin D3 diet administered during active colitis negatively affects bone metabolism in an adoptive T cell transfer model. Larmonier CB, McFadden RM, Hill FM, et al. Am. J. Physiol. Gastrointest. Liver Physiol. 305(1), G35-46, (2013)
Effect of different dosages of oral vitamin D supplementation on vitamin D status in healthy, breastfed infants: a randomized trial. Gallo S, Comeau K, Vanstone C, et al. JAMA 309(17), 1785-92, (2013)
Cholecalciferol supplementation in HIV-infected youth with vitamin D insufficiency: effects on vitamin D status and T-cell phenotype: a randomized controlled trial. Giacomet V, Vigano A, Manfredini V, et al. HIV Clin. Trials 14(2), 51-60, (2013)
Vitamin D in systemic lupus erythematosus: modest association with disease activity and the urine protein-to-creatinine ratio. Petri M, Bello KJ, Fang H, et al. Arthritis Rheum. 65(7), 1865-71, (2013)
Assessment of OPG/RANK/RANKL gene expression levels in peripheral blood mononuclear cells (PBMC) after treatment with strontium ranelate and ibandronate in patients with postmenopausal osteoporosis. Stuss M, Rieske P, Cegłowska A, et al. J. Clin. Endocrinol. Metab. 98(5), E1007-11, (2013)
Oral intake of phenylbutyrate with or without vitamin D3 upregulates the cathelicidin LL-37 in human macrophages: a dose finding study for treatment of tuberculosis. Mily A, Rekha RS, Kamal SM, et al. BMC Pulm. Med. 13, 23, (2013)
Changes in circulating 25-hydroxyvitamin D according to vitamin D binding protein genotypes after vitamin D₃ or D₂supplementation. Nimitphong H, Saetung S, Chanprasertyotin S, et al. Nutr. J. 12, 39, (2013)
Endothelial relaxation mechanisms and nitrative stress are partly restored by Vitamin D3 therapy in a rat model of polycystic ovary syndrome. Masszi G, Benko R, Csibi N, et al. Life Sci. 93(4), 133-8, (2013)
Aldrich MSDS 1, 1840:C / Corp MSDS 1 (2), 3609:A / FT-IR 2 (3), 4222:C / FT-IR 1 (2), 1049:D / FT-NMR 1 (3), 570:C / IR-Spectra (3), 1494:G / IR-Spectra (2), 1278:F / NMR-Reference 2 (2), 920:D / RegBook 1 (2), 2857:D / Sax 6, 787 / Sigma FT-IR 1 (1), 637:C / Structure Index 1, 457:B:7
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