E0518 Sigma

C1 Esterase Inhibitor from human plasma

aqueous solution, ≥95% (SDS-PAGE)

DOWNLOAD MSDS (PDF)

Synonym: Complement C1 esterase inhibitor, Esterase inhibitor C-1 from human plasma

Description

Physical form

Solution in 20 mM potassium phosphate, pH 7.0, containing 250 mM KCl

Biochem/physiol Actions

Esterase inhibitor C1 is a multifunctional regulator of all major kinin-generating protein cascade systems. It has been a therapeutic tool in the treatment of hereditary angioedema and complement-mediated inflammatory tissue damage such as capillary leak syndrome, septic shock, multiple organ failure, and hyperacute graft rejection.

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