|Related Categories||Cell Biology, Cell Culture, Cell Signaling and Neuroscience, Culture, Cytokine,|
|suitability||suitable for cell culture|
The biological activity is measured using a 3-day MTT assay.
A natural mitogenic growth factor used in cell culture applications to study cell signaling and to promote fibroblast and endothelial cell growth and survival.
Purified glands by a modification of the method of Gospodarowicz.
Although the major mitogenic component of this product is FGF2, the activity per unit weight of protein is less than that of purified FGF2.
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.1 mg/ml BSA.
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Isolation of brain fibroblast growth factor by heparin-Sepharose affinity chromatography: identity with pituitary fibroblast growth factor. Gospodarowicz, D., et al. Proc. Natl. Acad. Sci. U. S. A. 81, 6963-6967, (1984)
Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake. Tanaka T, Ngwa JS, van Rooij FJ, et al. Am. J. Clin. Nutr. 97(6), 1395-402, (2013)
Polymorphisms in FGF12, VCL, CX43 and VAX1 in Brazilian patients with nonsyndromic cleft lip with or without cleft palate. de Aquino SN, Messetti AC, Bagordakis E, et al. BMC Med. Genet. 14, 53, (2013)
Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism. Miraoui H, Dwyer AA, Sykiotis GP, et al. Am. J. Hum. Genet. 92(5), 725-43, (2013)
Cubilin, a high affinity receptor for fibroblast growth factor 8, is required for cell survival in the developing vertebrate head. Cases O, Perea-Gomez A, Aguiar DP, et al. J. Biol. Chem. 288(23), 16655-70, (2013)
Fibroblast growth factor-23 negates 1,25(OH)2D3-induced intestinal calcium transport by reducing the transcellular and paracellular calcium fluxes. Khuituan P, Wongdee K, Jantarajit W, et al. Arch. Biochem. Biophys. 536(1), 46-52, (2013)
PA21, a new iron-based noncalcium phosphate binder, prevents vascular calcification in chronic renal failure rats. Phan O, Maillard M, Peregaux C, et al. J. Pharmacol. Exp. Ther. 346(2), 281-9, (2013)
Paneth cells expand from newly created and preexisting cells during repair after doxorubicin-induced damage. King SL, Mohiuddin JJ, and Dekaney CM Am. J. Physiol. Gastrointest. Liver Physiol. 305(2), G151-62, (2013)
The fibroblast growth factor 14·voltage-gated sodium channel complex is a new target of glycogen synthase kinase 3 (GSK3). Shavkunov AS, Wildburger NC, Nenov MN, et al. J. Biol. Chem. 288(27), 19370-85, (2013)
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