|Related Categories||Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Cytoskeleton, Antibodies to Intermediate Filaments,|
|species reactivity||rat, pig, human|
|indirect immunofluorescence: 2.5-5 μg/mL using alcohol-fixed sections of rat brain/cerebellum.|
|western blot: suitable|
|antibody form||purified immunoglobulin|
|form||buffered aqueous solution|
|mol wt||antigen mol wt ~50 kDa|
|shipped in||dry ice|
human ... GFAP(2670)|
mouse ... Gfap(14580)
pig ... GFAP(396562)
rat ... Gfap(24387)
purified GFAP from pig spinal cord.
Glial fibrillary acidic protein or GFAP is a type III intermediate filament protein that is found in the astrocytes. GFAP assembly has been implicated in mitotic remodeling of glial structures. Genetic mutations in GFAP have been associated with Alexander disease 2,3
Monoclonal Anti-Glial Fibrillary Acidic Protein is specific for GFAP in rats, pigs and humans. The antibody does not bind to vimentin. The product stains glial cells, astrocytes Bergmann gliomas and other glial tumors by indirect immunofluorescence (using alcohol-fixed or frozen sections).
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Monoclonal Anti-Glial Fibrillary Acidic Protein antibody is suitable for use in western blot and indirect immunofluorescence 2.5-5 μg/mL using alcohol-fixed sections of rat brain/cerebellum). The antibody can also be used for immunoblot (approx. 50 kDa), immunohistochemistry (in paraformaldehyde-fixed, frozen rabbit brain sections1) and immunocytochemistry.
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Customers Also Viewed
purified immunoglobulin, buffered aqueous solution
~1 mg/mL, affinity isolated antibody, buffered aqueous solution
IgG fraction of antiserum, buffered aqueous solution
clone GFAP-B4, culture supernatant
clone G-A-5, ascites fluid
As a leading supplier of antibodies, Sigma® Life Science is committed to providing researchers the antibody they need with the quality they deserve. Our Antibody Explorer Search Tool provides easy ac...
Keywords: Buffers, Cell biology, Epigenetics, Immunohistochemistry, Immunoprecipitation, Molecular biology, Neuroscience, Western blot
3. Adult Alexander disease with autosomal dominant transmission: a distinct entity caused by mutation in the glial fibrillary acid protein gene. Stumpf, E., et al. Arch. Neurol. 60(9), 1307-12, (2003)
Reduced immunoproteasome formation and accumulation of immunoproteasomal precursors in the brains of lymphocytic choriomeningitis virus-infected mice. Kremer, M., et al. J. Immunol. 185, 5549-60, (2010)
Add to Cart
|G4546||Anti-Glial Fibrillary Acidic Protein antibody produced in rabbit, ~1 mg/mL, affinity isolated antibody, buffered aqueous solution|
|G9269||Anti-Glial Fibrillary Acidic Protein antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution|
|C9205||Monoclonal Anti-Glial Fibrillary Acidic Protein (GFAP)−Cy3™ antibody produced in mouse, clone G-A-5, purified immunoglobulin, buffered aqueous solution|
|G3893||Monoclonal Anti-Glial Fibrillary Acidic Protein (GFAP) antibody produced in mouse, clone G-A-5, ascites fluid|
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Need larger quantities for your development, manufacturing or research applications?