|Related Categories||Acid Glycoprotein, Application Index, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience,|
|assay||≥99% (agarose gel electrophoresis)|
|impurities||HIV-1/HIV-2, HCV and hepatitis B antigen, tested negative|
|Gene Information||human ... ORM2(5005)|
Purified from Cohn Fraction VI
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lyophilized powder, ≥97% (agarose gel electrophoresis)
lyophilized powder, Fatty acid free, Globulin free, ≥99% (agarose gel electrophoresis)
Despite their complexity, blood and plasma are abundant biological resources for the discovery of drug targets and biomarkers for human disease. It is estimated that plasma may contain as many as 40,...
BioFiles 2006, 1.5, 2.
Keywords: Gas chromatography
Development of large-scale fractionation methods. IV. A simple method for the large-scale preparation of alpha1-acid glycoprotein. Hao, Y.L. and Wickerhauser, M. Biochim. Biophys. Acta 322, 99, (1973)
Protein-bound polysaccharide decreases invasiveness and proliferation in pancreatic cancer by inhibition of hedgehog signaling and HIF-1α pathways under hypoxia. Onishi H, Morisaki T, Nakao F, et al. Cancer Lett. 335(2), 289-98, (2013)
Impact of adjuvant immunochemotherapy using protein-bound polysaccharide-K on overall survival of patients with gastric cancer. Tanaka H, Muguruma K, Ohira M, et al. Anticancer Res. 32(8), 3427-33, (2012)
Protein-bound polysaccharide-K (PSK) induces apoptosis via p38 mitogen-activated protein kinase pathway in promyelomonocytic leukemia HL-60 cells. Hirahara N, Edamatsu T, Fujieda A, et al. Anticancer Res. 32(7), 2631-7, (2012)
[Randomized phase II trial to compare S-1 and S-1/PSK for advanced or recurrent gastric cancer-lessons from the results]. Yoshikawa T, Tsuburaya A, Saze Z, et al. Gan To Kagaku Ryoho. 38(12), 1909-11, (2011)
Direct inhibition of the transforming growth factor-β pathway by protein-bound polysaccharide through inactivation of Smad2 signaling. Ono Y, Hayashida T, Konagai A, et al. Cancer Sci. 103(2), 317-24, (2012)
Anti-protein-bound polysaccharide-K monoclonal antibody binds the active structure and neutralizes direct antitumor action of the compound. Hoshi H, Saito H, Iijima H, et al. Oncol. Rep. 25(4), 905-13, (2011)
[A case of far-advanced gastric cancer successfully treated with S-1/paclitaxel/krestin immunochemotherapy, followed by curative resection]. Muguruma K, Tanaka H, Sakurai K, et al. Gan To Kagaku Ryoho. 39(12), 1770-2, (2012)
Polysaccharide-K augments docetaxel-induced tumor suppression and antitumor immune response in an immunocompetent murine model of human prostate cancer. Wenner CA, Martzen MR, Lu H, et al. Int. J. Oncol. 40(4), 905-13, (2012)
Biological mechanism and clinical effect of protein-bound polysaccharide K (KRESTIN(®)): review of development and future perspectives. Maehara Y, Tsujitani S, Saeki H, et al. Surg. Today 42(1), 8-28, (2012)
[Immunoregulatory effects of PSK on the Th1/Th2 balance and regulatory T-cells in patients with colorectal cancer]. Yoshino S, Yoshimura K, Suzuki N, et al. Gan To Kagaku Ryoho. 37(12), 2234-6, (2010)
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