|Related Categories||Bioactive Small Molecules, Cell Biology, Cell Culture, Cell Signaling and Neuroscience, Corticosteroid,|
|suitability||suitable for cell culture|
human ... ABCB1(5243), CYP3A4(1576), SERPINA6(866)|
mouse ... Abcb1a(18671), Abcb1b(18669), Ifng(15978), Nos2(18126)
rat ... Ar(24208), Nr3c1(24413)
Hydrocortisone for use in epithelial and endothelial adherent cell culture applications.
To prepare 50 μg/mL stock solution; add 1 mL absolute ethanol, gently swirl to dissolve, add 19 mL sterile medium while mixing.
powder-RT; stock-frozen in working aliquots, avoid repeated freeze/thaw
Primary glucocorticoid secreted by the adrenal cortex. It has three times the anti-inflammatory potency of corticosterone but much lower Na2+ retention potency.
Customers Also Viewed
~95% (SDS-PAGE), lyophilized powder, 1 × 105-1 × 106 units/mg protein
BioReagent, suitable for cell culture
meets USP testing specifications
50 μM, sterile-filtered, BioXtra, suitable for cell culture
Certificate of Analysis
Certificate of Origin
|Personal Protective Equipment||Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges|
|Hazard Codes (Europe)||Xn|
|Risk Statements (Europe)||63|
|Safety Statements (Europe)||36/37|
Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals. Markus A Lill et al J. Med. Chem. 48, 5666-74, (2005)
Microwave-enhanced nucleophilic fluorination in the synthesis of fluoropyridyl derivatives of [3,2-c]pyrazolo-corticosteroids, potential glucocorticoid receptor-mediated imaging agents. Michael G C Kahn et al Bioorg. Med. Chem. Lett. 16, 3454-8, (2006)
Design and synthesis of furoxan-based nitric oxide-releasing glucocorticoid derivatives with potent anti-inflammatory activity and improved safety. Lei Fang et al Bioorg. Med. Chem. Lett. 17, 1062-6, (2007)
Substrate competition studies using whole-cell accumulation assays with the major tripartite multidrug efflux pumps of Escherichia coli. Christopher A Elkins et al Antimicrob. Agents Chemother. 51, 923-9, (2007)
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Jenny M Pedersen et al J. Med. Chem. 51, 3275-87, (2008)
Protective effects of amide constituents from the fruit of Piper chaba on D-galactosamine/TNF-alpha-induced cell death in mouse hepatocytes. Hisashi Matsuda et al Bioorg. Med. Chem. Lett. 18, 2038-42, (2008)
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone. Edith Bellavance et al J. Med. Chem. 52, 7488-502, (2009)
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. Xiaofan Sui et al Eur. J. Med. Chem. 44, 4455-60, (2009)
Diarylheptanoids from Curcuma kwangsiensis and their inhibitory activity on nitric oxide production in lipopolysaccharide-activated macrophages. Jun Li et al Bioorg. Med. Chem. Lett. 21, 5363-9, (2011)
N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease. Gema C González-Muñoz et al Eur. J. Med. Chem. 46, 2224-35, (2011)
A small chemical library of 2-aminoimidazole derivatives as BACE-1 inhibitors: Structure-based design, synthesis, and biological evaluation. Gianpaolo Chiriano et al Eur. J. Med. Chem. 48, 206-13, (2012)
Corp MSDS 1 (1), 1894:B / FT-IR 2 (3), 4233:A / FT-NMR 1 (3), 584:C / RegBook 1 (2), 2863:G / Sigma FT-IR 1 (1), 1259:B / Structure Index 1, 458:D:6
Add to Cart
|H6909||Hydrocortisone solution, 50 μM, sterile-filtered, BioXtra, suitable for cell culture|
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Need larger quantities for your development, manufacturing or research applications?