|Related Categories||Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, GPCR Modulators,|
|Gene Information||human ... MTNR1A(4543), MTNR1B(4544)|
Melatonin metabolite with agonist activity.
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. H0627.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
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|Personal Protective Equipment||Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges|
|Hazard Codes (Europe)||Xn|
|Risk Statements (Europe)||22-40|
|Safety Statements (Europe)||36/37|
Longitudinal associations between endogenous melatonin production and reported sleep duration from childhood to early adulthood. Diethelm K, Libuda L, Bolzenius K, et al. Horm. Res. Paediatr. 74(6), 390-8, (2010)
The effects of melatonin, N-acetylserotonin, and 6-hydroxymelatonin on the ultrastructure of the pinealocytes of the Syrian hamster (Mesocricetus auratus). Zielińska A, Swietosławski J, Reiter RJ, et al. Endokrynol. Pol. 57(1), 2-6, (2006)
Oxidative DNA damage induced by a melatonin metabolite, 6-hydroxymelatonin, via a unique non-o-quinone type of redox cycle. Sakano K, Oikawa S, Hiraku Y, et al. Biochem. Pharmacol. 68(9), 1869-78, (2004)
The excretion of 6-hydroxymelatonin sulfate in healthy young men exposed to electromagnetic fields emitted by cellular phone -- an experimental study. Bortkiewicz A, Pilacik B, Gadzicka E, et al. Neuro Endocrinol. Lett. 23 Suppl 1, 88-91, (2002)
Prolonged inhibition of presynaptic catecholamine synthesis with alpha-methyl-para-tyrosine attenuates the circadian rhythm of human TSH secretion. Zimmermann RC, Krahn LE, Klee GG, et al. J. Soc. Gynecol. Investig. 8(3), 174-8, (2001)
Determination of exogenous melatonin and its 6-hydroxy metabolite in human plasma by liquid chromatography-mass spectrometry. Härtter S, Morita S, Bodin K, et al. Ther. Drug Monit. 23(3), 282-6, (2001)
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