Synonym: Hyaluronate Lyase from Streptomyces hyalurolyticus
|Related Categories||4.2.x.x C-O bonds, 4.x.x.x Lyases, Application Index, Biochemicals and Reagents, Carbohydrate Hydrolysis,|
|packaging||ampule of 300 × units|
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Hyaluronate lyase cleaves hyaluronic acid at the β-
One unit will cause a change in A600 of 0.330 per minute at pH 5.7 at 37°C in a 2.0 ml reaction mixture (45 minute assay).
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Certificate of Analysis
Certificate of Origin
Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units. The disaccharide units that are the basis of all glycosaminoglycans (except keratan) are a combination...
BioFiles 2008, 3.10, 4.
Keywords: Adhesion, Aminations, Angiogenesis, Anticoagulants, Apoptosis, Atomic absorption spectroscopy, Cancer, Cell biology, Cell proliferation, Cell signaling, Cellular processes, Central Nervous System, Chromatography, Coagulation, Degradations, Enzyme-linked immunosorbent assay, Epimerizations, Gene expression, Genetic, Genomics, Growth factors, High performance liquid chromatography, Inflammation, Ion-exchange chromatography, Ligands, Mass spectrometry, Microarray Analysis, Morphogenesis, Nuclear magnetic resonance spectroscopy, Phosphorylations, Polymerase chain reaction, Polymerization reactions, Proteomics, Reductive aminations, Spectroscopy, Sulfations, Transcription, transformation
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Efficient synthesis of an aldehyde functionalized hyaluronic acid and its application in the preparation of hyaluronan-lipid conjugates. Ruhela D, Riviere K, and Szoka FC Bioconjug. Chem. 17(5), 1360-3, (2006)
Role of ionic interactions and linker in the domain interaction and modulation of functional activity of hyaluronate lyases. Akhtar MS and Bhakuni V Biochem. Biophys. Res. Commun. 353(2), 286-92, (2007)
Mucins in the host defence against Naegleria fowleri and mucinolytic activity as a possible means of evasion. Cervantes-Sandoval I, Serrano-Luna Jde J, García-Latorre E, et al. Microbiology 154(Pt 12), 3895-904, (2008)
Modifying effects of morin on the development of aberrant crypt foci and bacterial enzymes in experimental colon cancer. Karthik Kumar V, Vennila S, and Nalini N Food Chem. Toxicol. 47(2), 309-15, (2009)
The Streptococcus equi prophage-encoded protein SEQ2045 is a hyaluronan-specific hyaluronate lyase that is produced during equine infection. Lindsay AM, Zhang M, Mitchell Z, et al. Microbiology 155(Pt 2), 443-9, (2009)
The Pic protease of enteroaggregative Escherichia coli promotes intestinal colonization and growth in the presence of mucin. Harrington SM, Sheikh J, Henderson IR, et al. Infect. Immun. 77(6), 2465-73, (2009)
Polysaccharide binding sites in hyaluronate lyase--crystal structures of native phage-encoded hyaluronate lyase and its complexes with ascorbic acid and lactose. Mishra P, Prem Kumar R, Ethayathulla AS, et al. FEBS J. 276(12), 3392-402, (2009)
Structures of two truncated phage-tail hyaluronate lyases from Streptococcus pyogenes serotype M1. Martinez-Fleites C, Smith NL, Turkenburg JP, et al. Acta Crystallogr. F, Struct. Biol. Cryst. Commun. 65(Pt 10), 963-6, (2009)
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