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H6894 Sigma

[Tyr(SO3H)63]-Hirudin Fragment 54-65

≥95% (HPLC)

DOWNLOAD MSDS (PDF)

  • CAS Number 109528-49-6

  • Empirical Formula (Hill Notation) C66H93N13O28S

  • Molecular Weight 1548.58

  •  MDL number MFCD00076564

  •  PubChem Substance ID 24895775

[Tyr(SO3H)63]-Hirudin Fragment 54-65 ≥95% (HPLC)
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Description

Amino Acid Sequence

Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr(SO3H)-Leu-Gln

Biochem/physiol Actions

Hirudin fragment that binds to the regulatory exosite I on thrombin and the regulatory proexosite I on prothrombin. The interaction with thrombin prevents the thrombin-induced activation of clotting factor V. The interaction with prothrombin inhibits the formation of thrombin by factor Xa in the presence of factor Va.

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