MISSION^® 3′UTR Lenti GoClone^™

Papers

Common micro RNAs (miRNAs) target complement factor H (CFH) regulation in Alzheimer’s disease (AD) and in age-related macular degeneration (AMD) Lukiw, W., et al. Int. J. Biochem. 1st ed., 3, 105-116, (2012)

Identification and functional analysis of human transcriptional promoters. Trinklein, N.D., et al. Genome Res. 13, 308-312, (2003)

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The ENCODE (ENCyclopedia Of DNA Elements) Project. ENCODE Project Consortium. Science 306, 636-640, (2004)

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The role of heat shock transcription factor 1 in the genome-wide regulation of the mammalian heat shock response. Trinklein, N.D., et al. Mol. Biol. Cell 15, 1254-1261, (2004)

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An abundance of bidirectional promoters in the human genome. Trinklein, N.D., et al. Genome Res. 14, 62-66, (2004)

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Transcriptional regulation and binding of heat shock factor 1 and heat shock factor 2 to 32 human heat shock genes during thermal stress and differentiation. Trinklein, N.D., et al. Cell Stress Chaperones 9, 21-28, (2004)

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Direct isolation and identification of promoters in the human genome. Kim, T.H., et al. Genome Res. 15, 830-839, (2005)

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Comprehensive Analysis of Transcriptional Promoter Structure and Function in 1% of the Human Genome. Cooper, S.J., et al. Genome Res. 16, 01-010, (2005)

Polymorphisms within the C-reactive protein (CRP) promoter region are associated with plasma CRP levels. Carlson, C.S., et al. Am. J. Hum. Genet. 77, 64-77, (2005)

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Over-represented sequences located on 3’ UTRs are potentially involved in regulatory functions. Yoon, K., et al. RNA Biol. 5, 255-262, (2008)

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Insulin Enhances The Biogenesis Of Nuclear Sterol Regulatory Element-binding Protein (SREBP)-1c By Posttranscriptional Down-regulation Of Insig-2A And Its Dissociation From SREBP Cleavage-activating Protein (SCAP)·SREBP-1c Complex Yellaturu, C., et al. J. Biol. Chem. 284, 31726 - 31734, (2009)

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Gene Product Modulates TIS11B Expression in Renal Cell Carcinoma:Impact on Vascular Endothelial Growth Factor Expression in Hypoxia. Sinha, S., et al. J. Biol. Chem. 284, 32610-32618, (2009)

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Distinct MicroRNA Alterations Characterize High- and Low-Grade Bladder Cancer. Catto, J., et al. Cancer Res. 69, 8472-8481, (2009)

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Identification of Chemical Compunds that induce HIF-1alpha Activity. Xia, M., et al. Toxicol. Sci. 112, 153-163, (2009)

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Overlapping promoter targeting by Elk-1 and other divergent ETS-domain transcription factor family members. Boros, J., et al. Nucleic Acids Res. 37, 7368-7380, (2009)

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KLF4 suppresses HDACi induced caspase activation and the SAPK pathway by targeting p57. Ky, N., et al. Apoptosis 14, 1095-1107, (2009)

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Caveolin-1 Promotes Autoregulatory, Akt-Mediated Induction of Cancer-Promoting Growth Factors in Prostate Cancer Cells. Li, L., et al. Mol. Cancer Res. 7, 1781-1791, (2009)

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Pathway Reporter Assays Reveal Small Molecule Mechanisms of Action. King, F., et al. J. Assoc. Lab. Autom. 14, 374-382, (2009)

Functional profiling reveals critical role for miRNA in Differentiation of Human Mesenchymal Stem Cells Schoolmeesters, A., et al. PLoS ONE 4, e5605, (2009)

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A functional analysis of the CREB signaling pathway using HaloCHIP-chip and high throughput reporter assays. Hartzell, D., et al. BMC Genomics 10, 497, (2009)

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MicroRNAs in the miR-106b Family Regulate p21/CDKN1A and Promote Cell Cycle Progression. Ivanovska, I., et al. Mol. Cell. Biol. 28, 2167-2174, (2008)

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MicroRNAs Distinguish Translational from Transcriptional Silencing during Endotoxin Tolerance. El Gazzar, M., et al. J. Biol. Chem. 285, 20940-20951, (2010)

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Regulation of Heme Oxygenase-1 Protein Expression by miR-377 in Combination with miR-217. Beckman, J., et al. J. Biol. Chem. 286, 3194-3202, (2010)

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hsa-miR-191 Is a Candidate Oncogene Target for Hepatocellular Carcinoma Therapy Eran Elyakimet, et al. Cancer Res. 70, 8077-8087, (2010)

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GIP increases human adipocyte LPL expression through CREB and TORC2-mediated trans-activation of the LPL gene. Kim, S., et al. J. Lipid Res. 51, 3145-3157, (2010)

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MicroRNA-205–directed transcriptional activation of tumor suppressor genes in prostate cancer. Majid, S., et al. Cancer 116, 5637-5649, (2010)

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Estradiol Suppresses NF-κB Activation through Coordinated Regulation of let-7a and miR-125b in Primary Human Macrophages. Murphy, A., et al. J. Immunol. 184, 5029-5037, (2010)

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The T-box transcription factor Brachyury promotes epithelial-mesenchymal transition in human tumor cells. Fernando, R., et al. J. Clin. Invest. 120, 533-544, (2010)

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The Endothelial-Dependent Effect of RTEF-1 in Pressure Overload Cardiac Hypertrophy – Role of VEGF-B. Xu, M., et al. Cardiovasc. Res. 90(2), 325-334, (2010)

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G-protein-coupled receptor for short-chain fatty acids suppresses colon cancer. Tang, Y., et al. Int. J. Cancer 128, 847-856, (2010)

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Transcriptome and targetome analysis in MIR155 expressing cells using RNA-Seq. Xu, G., et al. RNA 16, 1610-1622, (2010)

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The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-β Pathway in Neuroblastoma. Mestdagh., et al. Mol. Cell. 40, 762-773, (2010)

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Glycogen synthase kinase-3β inhibitors suppress leukemia cell growth Songab, E., et al. Exp. Hematol. 38, 908-921.e1, (2010)

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microRNAs regulate human embryonic stem cell division Qi., et al. Cell Cycle 8, 3729-3741, (2010)

MicroRNA-210 Regulates Mitochondrial Free Radical Response to Hypoxia and Krebs Cycle in Cancer Cells by Targeting Iron Sulfur Cluster Protein ISCU. Favaro, E., et al. PLoS ONE 5, e10345, (2010)

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14-3-3τ Regulates Beclin 1 and Is Required for Autophagy. Wang, B., et al. PLoS ONE 5, e10409, (2010)

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Characterization of the Contradictory Chromatin Signatures at the 3' Exons of Zinc Finger Genes. Blahnik., et al. PLoS ONE 6, e17121, (2010)

Phospho-δNp63α/Rpn13-dependent regulation of LKB1 degradation modulates autophagy in cancer cells. Huang, Y., et al. Aging 2, 959-968, (2010)

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Suppression of Latent TGF-beta1 Restores Growth Inhibitory TGFBeta Signaling Through microRNAs. Dogar, A., et al. J. Biol. Chem. 286, 16447-16458, (2011)

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A Two-Tiered Approach Identifies a Network of Cancer and Liver Diseases Related Genes Regulated by miR-122. Boutz, D., et al. J. Biol. Chem. 286, 18066-18078, (2011)

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The miR-183-96-182 cluster is overexpressed in prostate tissue and regulates zinc homeostasis in prostate cells Nonn., et al. J. Biol. Chem., (2011)

Inhibition of miR-193a expression by Max and RXRα activates K-Ras and PLAU to mediate distinct aspects of cellular transformation Iliopoulos, D., et al. Cancer Res. 18, 1619-1629, (2011)

IL-8 signaling plays a critical role in the epithelial-mesenchymal transition of human carcinoma cells Fernando, R., et al. Cancer Res. 71, 5296, (2011)

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Acquired STAT4 Deficiency as a Consequence of Cancer Chemotherapy Chang, H., et al. Blood 118(23), 6097-6106, (2011)

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Genome-wide microRNA downregulation as a negative feedback mechanism in the early phases of liver regeneration Shu, J., et al. Hepatology 54, 609-619, (2011)

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A Comprehensive Analysis of MicroRNA ExpressionDuring Human Keratinocyte Differentiation In Vitro and In Vivo. Hildebrand, J., et al. J. Invest. Dermatol. 131, 20-29, (2011)

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A novel epidermal growth factor receptor variant lacking multiple domains directly activates transcription and is overexpressed in tumors Wong, et al. Oncogene, (2011)

The nuclear receptor TR3 regulates mTORC1 signaling in lung cancer cells expressing wild-type p53 Lee, S.O., et al. Oncogene, (2011)

The oxysterol 27-hydroxycholesterol regulates α-synuclein and tyrosine hydroxylase expression levels in human neuroblastoma cells through modulation of liver X receptors and estrogen receptors–relevance to Parkinson’s disease Marwarha, G., et al. J. Neurochem. 119, 1119-1136, (2011)

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Effect of Brain- and Tumor-Derived Connective Tissue Growth Factor on Glioma Invasion Edwards, L., et al. J. Natl. Cancer Inst. 103(15), 1162-1178, (2011)

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Porphyromonas gingivalis induction of microRNA-203 expression controls suppressor of cytokine signaling 3 in gingival epithelial cells Moffat, C., et al. Infect. Immun., (2011)

An extended set of PRDM1/BLIMP1 target genes links binding motif type to dynamic repression. Doody, G., et al. Nucleic Acids Res. 39, 4564-4576, (2011)

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Endoplasmic reticulum stress-induced CHOP activation mediates the down-regulation of leptin in human neuroblastoma SH-SY5Y cells treated with the oxysterol 27-hydroxycholesterol Marwarha, G., et al. Cell. Signal. 24, 484-492, (2011)

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Dickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastoma De Brouwer, S., et al. Int. J. Cancer 130, 2591-2598, (2011)

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Identification of a pH-responsive DNA region upstream of the transcription start site of human NBCe1-B Snead, C. M., et al. Eur. J. Oral Sci. 119, 136-141, (2011)

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Deregulation of microRNA-503 Contributes to Diabetes Mellitus–Induced Impairment of Endothelial Function and Reparative Angiogenesis After Limb Ischemia Caporali, A., et al. Circulation 123, 282-291, (2011)

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MicroRNA-132 targets HB-EGF upon IgE-mediated activation in murine and human mast cells Molnár, V., et al. Cell. Mol. Life Sci. 69, 793-808, (2011)

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Neurotensin Signaling Activates MicroRNAs-21 and-155 and Akt, Promotes Tumor Growth in Mice, and is Increased in Human Colon Tumors Bakirtzi, K., et al. Gastroenterology 141, 1749-1761, (2011)

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p53 Directly Represses Id2 to Inhibit the Proliferation of Neural Progenitor Cells Paolella, B., et al. Stem Cells 29, 1090-1101, (2011)

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Identification, Replication, and Functional Fine-Mapping of Expression Quantitative Trait Loci in Primary Human Liver Tissue Innocenti, F., et al. PLoS Genet. 7, e1002078, (2011)

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Prediction of Associations between microRNAs and Gene Expression in Glioma Biology Wuchty., et al. PLoS ONE 6, e14681, (2011)

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Effects of Thai Medicinal Herb Extracts with Anti-Psoriatic Activity on the Expression on NF-κB Signaling Biomarkers in HaCaT Keratinocytes Saelee, C., et al. Molecules 16, 3908-3932, (2011)

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The novel function of HINFP as a co-activator in sterol-regulated transcription of PCSK9 in HepG2 cells Li, H., et al. Biochem. J. 443, 757-768, (2012)

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MicroRNA-29b is involved in the Src-ID1 signaling pathway and is dysregulated in human lung adenocarcinoma Rothschild, S.I., et al. Oncogene, (2012)

Transcriptional provirus silencing as a crosstalk of de novo DNA methylation and epigenomic features at the integration site Šenigl, F., et al. Nucleic Acids Res., (2012)

MicroRNA-199a* regulates the expression of cyclooxygenase-2 in human chondrocytes Akhtar, N., et al. Ann. Rheum. Dis., (2012)

The Mitochondrial ATPase Inhibitory Factor 1 Triggers a ROS-Mediated Retrograde Prosurvival and Proliferative Response Formentini, L., et al. Mol. Cell. 45, 731-742, (2012)

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miR-125 potentiates early neural specification of human embryonic stem cells Boissart, C., et al. Development 139, 1247-1257, (2012)

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The neuroimmune guidance cue netrin-1 promotes atherosclerosis by inhibiting the emigration of macrophages from plaques van Gils, J., et al. Nat. Immunol. 13, 136-143, (2012)

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Antiproliferative Factor Regulates Connective Tissue Growth Factor (CTGF/CCN2) Expression in T24 Bladder Carcinoma Cells Matika, C.A., et al. Molecular Biology of the Cell, (2012)

MicroRNA-200b Regulates Cell Proliferation, Invasion, and Migration by Directly Targeting ZEB2 in Gastric Carcinoma Baba, H., et al. Ann. Surg. Oncol., (2012)