I0904 Sigma

Interleukin-2 Soluble Receptor β human

>97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder

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Synonym: IL-2 sRα

Description

Analysis Note

The bioactivity is measured by its ability to inhibit the IL-15-dependent proliferation of a human megakaryocytic leukemic cell line, M07e.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.25 mg bovine serum albumin.

Biochem/physiol Actions

Recombinant human IL-2 soluble receptor β is a member of the cytokine receptor superfamily. It binds IL-2 with low affinity but will bind IL-15 sufficiently for neutralization activities.

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