Iturin A from Bacillus subtilis
≥95% (HPLC)
DOWNLOAD MSDS (PDF)-
CAS Number 52229-90-0
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MDL number MFCD01094135
Properties
| Related Categories | Antibiotics, Antibiotics A to Z, Antibiotics G-M, Antifungal, Biochemicals and Reagents, |
| assay | ≥95% (HPLC) |
| storage temp. | 2-8°C |
Description
Biochem/physiol Actions
Iturin A exhibits strong antifungal activity against pathogenic yeast and fungi.1 It interacts with the cytoplasmic membrane of the target cell forming ion conducting pores2 and its mode of action could be attributed to its interaction with sterols and phospholipids. The compound causes the release of exo-vesicles from human erythrocytes.3
Other Notes
A family of lipopeptides characterized by a heptapeptide cyclized with a C13-C17 β-amino fatty acid. Composed mainly of C14-C15 β-amino acids.
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