|Related Categories||Antibiotics, Antibiotics A to Z, Antibiotics G-M, Antifungal, Biochemicals and Reagents,|
Iturin A exhibits strong antifungal activity against pathogenic yeast and fungi.1 It interacts with the cytoplasmic membrane of the target cell forming ion conducting pores2 and its mode of action could be attributed to its interaction with sterols and phospholipids. The compound causes the release of exo-vesicles from human erythrocytes.3
A family of lipopeptides characterized by a heptapeptide cyclized with a C13-C17 β-amino fatty acid. Composed mainly of C14-C15 β-amino acids.
3. Thimon, L., et al. Cytobios. 79, 96, (1994)
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