|Related Categories||Antibiotics, Antibiotics A to Z, Antibiotics G-M, Antifungal, Biochemicals and Reagents,|
Iturin A exhibits strong antifungal activity against pathogenic yeast and fungi.1 It interacts with the cytoplasmic membrane of the target cell forming ion conducting pores2 and its mode of action could be attributed to its interaction with sterols and phospholipids. The compound causes the release of exo-vesicles from human erythrocytes.3
A family of lipopeptides characterized by a heptapeptide cyclized with a C13-C17 β-amino fatty acid. Composed mainly of C14-C15 β-amino acids.
3. Thimon, L., et al. Cytobios. 79, 96, (1994)
Co-producing iturin A and poly-γ-glutamic acid from rapeseed meal under solid state fermentation by the newly isolated Bacillus subtilis strain 3-10. Yao D, Ji Z, Wang C, et al. World J. Microbiol. Biotechnol. 28(3), 985-91, (2012)
The ultrasound-assisted extraction and identification of antifungal substances from B. amyloliquefaciens strain NJN-6 suppressing Fusarium oxysporum. Yuan J, Raza W, Huang Q, et al. J. Basic Microbiol. 52(6), 721-30, (2012)
The complete genome of Bacillus amyloliquefaciens subsp. plantarum CAU B946 contains a gene cluster for nonribosomal synthesis of iturin A. Blom J, Rueckert C, Niu B, et al. J. Bacteriol. 194(7), 1845-6, (2012)
Quantification of the antifungal lipopeptide iturin A by high performance liquid chromatography coupled with aqueous two-phase extraction. Yuan J, Raza W, Huang Q, et al. J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 879(26), 2746-50, (2011)
Bacillus subtilis SSE4 produces subtulene A, a new lipopeptide antibiotic possessing an unusual C15 unsaturated beta-amino acid. Thasana N, Prapagdee B, Rangkadilok N, et al. FEBS Lett. 584(14), 3209-14, (2010)
Production of biosurfactant lipopeptides Iturin A, fengycin and surfactin A from Bacillus subtilis CMB32 for control of Colletotrichum gloeosporioides. Kim PI, Ryu J, Kim YH, Chi YT. J. Microbiol. Biotechnol. 20, 138-145, (2010)
Molecular and biochemical approaches for characterization of antifungal trait of a potent biocontrol agent Bacillus subtilis RP24. Grover M, Nain L, Singh SB, et al. Curr. Microbiol. 60(2), 99-106, (2010)
Cell surface hydrophobicity of Bacillus spp. as a function of nutrient supply and lipopeptides biosynthesis and its role in adhesion. Czaczyk K, Białas W, and Myszka K Pol. J. Microbiol. 57(4), 313-9, (2008)
Insights into the defense-related events occurring in plant cells following perception of surfactin-type lipopeptide from Bacillus subtilis. Jourdan E, Henry G, Duby F, et al. Mol. Plant Microbe Interact. 22(4), 456-68, (2009)
Microbial analysis of a composted product of marine animal resources and isolation of bacteria antagonistic to a plant pathogen from the compost. Niisawa C, Oka S, Kodama H, et al. J. Gen. Appl. Microbiol. 54(3), 149-58, (2008)
Medium optimization of antifungal lipopeptide, iturin A, production by Bacillus subtilis in solid-state fermentation by response surface methodology. Mizumoto S and Shoda M Appl. Microbiol. Biotechnol. 76(1), 101-8, (2007)
Enhanced iturin A production by Bacillus subtilis and its effect on suppression of the plant pathogen Rhizoctonia solani. Mizumoto S, Hirai M, and Shoda M Appl. Microbiol. Biotechnol. 75(6), 1267-74, (2007)
The iturin and fengycin families of lipopeptides are key factors in antagonism of Bacillus subtilis toward Podosphaera fusca. Romero D, de Vicente A, Rakotoaly RH, et al. Mol. Plant Microbe Interact. 20(4), 430-40, (2007)
Antimicrobial factor from Bacillus amyloliquefaciens inhibits Paenibacillus larvae, the causative agent of American foulbrood. Benitez LB, Velho RV, de Souza da Motta A, et al. Arch. Microbiol. 194(3), 177-85, (2012)
Bacillus amyloliquefaciens GA1 as a source of potent antibiotics and other secondary metabolites for biocontrol of plant pathogens. Arguelles-Arias A, Ongena M, Halimi B, et al. Microb. Cell Fact. 8, 63, (2009)
Iturin A is the principal inhibitor in the biocontrol activity of Bacillus amyloliquefaciens PPCB004 against postharvest fungal pathogens. Arrebola E, Jacobs R, and Korsten L J. Appl. Microbiol. 108(2), 386-95, (2010)
Study of the antifungal activity of Acinetobacter baumannii LCH001 in vitro and identification of its antifungal components. Liu CH, Chen X, Liu TT, et al. Appl. Microbiol. Biotechnol. 76(2), 459-66, (2007)
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