|Related Categories||Antagonist, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience,|
|Gene Information||human ... TACR2(6865)|
Potent and selective NK-2 tachykinin receptor antagonist.
Bottomless glass bottle. Contents are inside inserted fused cone.
Certificate of Analysis
The tachykinins represent a large family of peptides whose common structural feature is the C-terminal amino acid sequence Phe-X-Gly-Leu-Met.NH2. Substance P (SP), neurokinin A (NKA), neurokinin B (N...
Effects of tachykinins on rapidly adapting pulmonary stretch receptors and total lung resistance in anesthetized, artificially ventilated rabbits. Matsumoto S, Takeda M, Saiki C, et al. J. Pharmacol. Exp. Ther. 283(3), 1026-31, (1997)
In vivo role of the adenosine A3 receptor: N6-2-(4-aminophenyl)ethyladenosine induces bronchospasm in BDE rats by a neurally mediated mechanism involving cells resembling mast cells. Meade CJ, Mierau J, Leon I, et al. J. Pharmacol. Exp. Ther. 279(3), 1148-56, (1996)
Pharmacological characterization of GR82334, a tachykinin NK1 receptor antagonist, in the isolated spinal cord of the neonatal rat. Guo JZ, Yoshioka K, Zhao FY, et al. Eur. J. Pharmacol. 281(1), 49-54, (1995)
Comparative conformational analysis and in vitro pharmacological evaluation of three cyclic hexapeptide NK-2 antagonists. Wollborn U, Brunne RM, Harting J, et al. Int. J. Pept. Protein Res. 41(4), 376-84, (1993)
Characterization of the tachykinin NK2 receptor in the human bronchus: influence of amastatin-sensitive metabolic pathways. Astolfi M, Treggiari S, Giachetti A, et al. Br. J. Pharmacol. 111(2), 570-4, (1994)
Pharmacological analysis of receptors involved in tachykininergic contraction induced by electrical transmural stimulation in the rabbit iris sphincter muscle. Kunitomo M, Imaizumi N, Sameshima E, et al. Regul. Pept. 46(1-2), 282-4, (1993)
Effect of scyliorhinin I and synthetic scyliorhinin I derivatives at mammalian tachykinin NK1, NK2 and NK3 receptors. Patacchini R, Quartara L, Rolka K, et al. Eur. J. Pharmacol. 250(2), 311-6, (1993)
[125I]His-neurokinin A binds selectively to NK2 receptors of the B-type in rat small intestine smooth muscle membranes. Brown MC, Biagi M, Renzetti AR, et al. Eur. J. Pharmacol. 227(2), 163-71, (1992)
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