Synonym: 3β-Hydroxy-8,24-lanostadiene, 8,24-Lanostadien-3β-ol
|Related Categories||Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Cholesterol and Cholesterol Metabolism,|
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Cholesterol precursor sterol
Certificate of Analysis
Certificate of Origin
Cholesterol levels in the body come from two sources, dietary intake and biosynthesis. The majority of cholesterol utilized by healthy adults is synthesized in the liver, which produces ~70% of the t...
BioFiles 2007, 2.7, 3.
Keywords: Catalysis, Decarboxylations, Metabolic Pathways, Oxidations, PAGE, Phosphorylations, Reductions
Production of Ginkgo leaf-shaped basidiocarps of the Lingzhi or Reishi medicinal mushroom Ganoderma lucidum (higher Basidiomycetes), containing high levels of α- and β-D-glucan and ganoderic acid A. Yajima Y, Miyazaki M, Okita N, et al. Int. J. Med. Mushrooms 15(2), 175-82, (2013)
Protective effect of ganodermanondiol isolated from the Lingzhi mushroom against tert-butyl hydroperoxide-induced hepatotoxicity through Nrf2-mediated antioxidant enzymes. Li B, Lee DS, Kang Y, et al. Food Chem. Toxicol. 53, 317-24, (2013)
The role of PKC/ERK1/2 signaling in the anti-inflammatory effect of tetracyclic triterpene euphol on TPA-induced skin inflammation in mice. Passos GF, Medeiros R, Marcon R, et al. Eur. J. Pharmacol. 698(1-3), 413-20, (2013)
Friedelin and lanosterol from Garcinia prainiana stimulated glucose uptake and adipocytes differentiation in 3T3-L1 adipocytes. Susanti D, Amiroudine MZ, Rezali MF, et al. Nat. Prod. Res. 27(4-5), 417-24, (2013)
Five new 3,4-seco-lanostane-type triterpenoids with antiproliferative activity in human leukemia cells isolated from the roots of Kadsura coccinea. Wang N, Li ZL, Song DD, et al. Planta Med. 78(15), 1661-6, (2012)
Lanosterol biosynthesis: the critical role of the methyl-29 group of 2,3-oxidosqualene for the correct folding of this substrate and for the construction of the five-membered D ring. Hoshino T, Chiba A, and Abe N Chemistry 18(41), 13108-16, (2012)
Euphol, a tetracyclic triterpene produces antinociceptive effects in inflammatory and neuropathic pain: the involvement of cannabinoid system. Dutra RC, Simão da Silva KA, Bento AF, et al. Neuropharmacology 63(4), 593-605, (2012)
Antileukemia component, dehydroeburicoic acid from Antrodia camphorata induces DNA damage and apoptosis in vitro and in vivo models. Du YC, Chang FR, Wu TY, et al. Phytomedicine 19(8-9), 788-96, (2012)
Potential biological functions of cytochrome P450 reductase-dependent enzymes in small intestine: novel link to expression of major histocompatibility complex class II genes. D'Agostino J, Ding X, Zhang P, et al. J. Biol. Chem. 287(21), 17777-88, (2012)
Sterol C24-methyltransferase: Physio- and stereo-chemical features of the sterol C3 group required for catalytic competence. Howard AL, Liu J, Elmegeed GA, et al. Arch. Biochem. Biophys. 521(1-2), 43-50, (2012)
HILIC quantification of oenotheralanosterol A and B from Oenothera biennis and their suppression of IL-6 and TNF-α expression in mouse macrophages. Singh R, Trivedi P, Bawankule DU, et al. J. Ethnopharmacol. 141(1), 357-62, (2012)
Insulin-induced gene protein (INSIG)-dependent sterol regulation of Hmg2 endoplasmic reticulum-associated degradation (ERAD) in yeast. Theesfeld CL and Hampton RY J. Biol. Chem. 288(12), 8519-30, (2013)
Euphol from Euphorbia tirucalli selectively inhibits human gastric cancer cell growth through the induction of ERK1/2-mediated apoptosis. Lin MW, Lin AS, Wu DC, et al. Food Chem. Toxicol. 50(12), 4333-9, (2012)
Structure determination of inonotsuoxides A and B and in vivo anti-tumor promoting activity of inotodiol from the sclerotia of Inonotus obliquus. Tomoko Nakata et al Bioorg. Med. Chem. 15, 257-64, (2007)
Expression, purification, and characterization of Aspergillus fumigatus sterol 14-alpha demethylase (CYP51) isoenzymes A and B. Andrew G S Warrilow et al Antimicrob. Agents Chemother. 54, 4225-34, (2010)
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