|Related Categories||Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, CI-CY, Cell Biology, Cell Signaling and Neuroscience,|
|color||white to off-white|
|solubility||DMSO: ≥20 mg/mL|
|storage temp.||room temp|
Sold for research purposes under agreement from Pfizer Inc.
CP-471474 is a broad spectrum inhibitor of matrix metalloproteinases. CP-471474 has a low nM IC50 efficacy for MMP-2, MMP-3, MMP-9, and MMP-13. CP-471474 has low potency against MMP-1 (IC50 > 1 uM). CP-471474 prevents left ventricular remodeling after experimental myocardial infarction in mice. CP-471474 also inhibits cigarette smoke-induced lung inflammation and the progression of emphysema in guinea pig models.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Need larger quantities for your development, manufacturing or research applications?