|Related Categories||Antioxidant, Chemical Synthesis, Functional Foods, Inorganic Salts, Nutrition Research,|
|suitability||suitable for cell culture|
Sodium selenite is commonly used as a source of selenium in biological research, where selenium is an essential trace element that is normally provided by serum. Selenium is present in selenoproteins such as glutathione peroxidase and thioredoxin reductase, which contain the selenium analog of cysteine, selenocysteine. In particular, glutathione peroxidase has a role in detoxification in vivo as a scavenger of peroxides. Sodium selenite has been utilized in studies of cell proliferation and cancer research. It has been used to alter gene expression in HepG2 cells as analyzed by cDNA microarrays. Sodium selenite can inhibit zinc finger protein/DNA interactions. Sodium selenite has been shown to alter mitochondrial membrane potentials and thus potentially contribute to apoptosis.
This product is cell culture tested (0.005 mg/L) and is appropriate for use in cell culture applications.
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Certificate of Analysis
Certificate of Origin
|Precautionary statements||P261-P264-P273-P280-P301 + P310-P311|
|Supplemental Hazard Statements||Contact with acids liberates toxic gas.|
|Personal Protective Equipment||Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges|
|Hazard Codes (Europe)||T+,N|
|Risk Statements (Europe)||23-28-31-43-51/53|
|Safety Statements (Europe)||28-36/37-45-61|
|RIDADR||UN 2630 6.1/PG 1|
Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.1 During the oxi...
BioFiles 2007, 2.2, 2.
Keywords: Adhesion, Anti-inflammatory agents, Cancer, Cardiovascular, Catalysis, Diabetes, Diseases, Gene expression, Metabolism, Neurodegenerative Diseases, Peroxidations, Phosphorylations, Prebiotics, Probiotics, Reductions, Transcription, Transduction, Vitamins
Aldrich MSDS 1, 1614:B / Corp MSDS 1 (2), 3153:D / RegBook 1 (3), 3509:H / Sax 6, 2451 / Sigma FT-IR 1 (2), 1047:B
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