Synonym: BRCAI, BRCC1, BROVCA1, IRIS, PNCA4, PSCP, RNF53
|Related Categories||Cell Biology, Cell Signaling and Neuroscience, Gene Regulation and Expression, Transcription Factors|
|recombinant||expressed in insect cells|
|mol wt||mol wt ~209 kDa|
|NCBI accession no.||NM_007296|
|shipped in||dry ice|
|Gene Information||human ... BRCA1(672)|
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.
Clear and colorless frozen liquid solution
The human BRCA1, the product of breast and ovarian cancer gene 1, is a hyperphosphorylated protein functioning as a tumor suppressor involved in both transcription regulation and DNA repair. BRCA1 associates with RAD51 and has shown to be required for transcription-coupled repair of DNA damage as well as for the repair of chromosomal double-strand breaks. Association with a human SWI/SNF-related complex has recently suggested a potential role of BRCA1 in linking chromatin remodeling to breast cancer.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Need larger quantities for your development, manufacturing or research applications?