IL-17D human
recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
DOWNLOAD MSDS (PDF)Synonym: IL-27
Properties
| Related Categories | Cancer Research, Cell Biology, Cell Signaling and Neuroscience, Cytokines, Cytokines & Growth Factors, |
| recombinant | expressed in E. coli |
| assay | ≥98% (HPLC) |
| ≥98% (SDS-PAGE) | |
| form | lyophilized |
| mol wt | mol wt 40.5 kDa |
| impurities | endotoxin, tested |
| suitability | cell culture tested |
Description
Biochem/physiol Actions
IL-17D is a disulfide-linked homodimer of two 185 amino acid polypeptide chains. Recombinant human IL-17D is a 40.5 kDa disulfide-linked homodimer of two 185 amino acid polypeptide chains.
Reconstitution
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.5-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Physical form
Lyophilized from 1x PBS, pH 7.2.
General description
IL-17D is a disulfide-linked homodimer of two 185 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17D has the ability to stimulate the production of IL-6, IL-8, and GM-CSF and inhibits hemopoiesis of myeloid progenitor cells in colony forming assays. Recombinant human IL-17D is a 40.5 kDa disulfide-linked homodimer of two 185 amino acid polypeptide chains.
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