Isopeptidase T (short form) human
recombinant, expressed in E. coli, ≥95% (SDS-PAGE)
DOWNLOAD MSDS (PDF)Synonym: Isoopeptidase T, Isopeptidase T (short form), IsopeptidaseT, USP5, Ubiquitin-specific protease 5
Properties
| Related Categories | Cell Biology, Cell Signaling and Neuroscience, Intracellular Protein Degradation, Nitric Oxide and Cell Stress, Ubiquitin and Proteases More... |
| recombinant | expressed in E. coli |
| assay | ≥95% (SDS-PAGE) |
| form | liquid |
| mol wt | mol wt 93.4 kDa |
| concentration | ~2.0 mg/mL |
| impurities | Endotoxin, tested |
| NCBI accession no. |
P45974
|
Description
General description
Ubiquitin C-terminal hydrolases (UCHs) are a family of cysteine hydrolases that catalyze the UBPs hydrolyze isopeptide bonds between ubiquitin and the substrate protein or within polyubiquitin chains. Human isopeptidase T (isoT) is an UBP capable of binding ubiquitin that specifically disassembles free polyubiquitin chains linked through isopeptide bonds involving the K48 of ubiquitin into ubiquitin monomers.
Physical form
Supplied at a concentration of 2.0 mg/ml in 50 mM Tris, 10 mM ?-mercaptoethanol, pH 7.5.
Price and Availability
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