(±)-Taxifolin hydrate ≥90% (HPLC)

Properties

Related Categories	A to C, Antioxidants and Cytoprotectants, Bioactive Small Molecules, Biochemicals and Reagents, Cancer Metabolism, Cancer Research, Casein Kinase G, Cell Biology, Cell Signaling and Neuroscience, Cell Stress, Cytochrome P450, D to K, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Fatty Acid Metabolism in Oncogenesis, Fatty Acid Synthase (FAS) Inhibitors, Flavonoids, Flavonols, and Flavanols, Glutathione S-transferase, Inhibitors and Activators of Fatty Acid Metabolism, Nitric Oxide and Cell Stress, Nutrition Research, Phytochemicals by Chemical Classification, T More...
assay	≥90% (HPLC)
solubility	DMSO: soluble20 mg/mL
storage temp.	−20°C
Gene Information	mouse ... Hexa(15211)

Description

Biochem/physiol Actions

Flavonoid, antioxidant. Inhibits lipogenesis in cancer cells, most likely by targeting fatty acid synthase activity.

Price and Availability

Related Papers

Antiradical and chelating effects in flavonoid protection against silica-induced cell injury. Kostyuk, V.A., Potapovich, A.I. Arch. Biochem. Biophys. 355, 43, (1998)

Documents

Certificate of Analysis

Certificate of Origin

Safety Information

Symbol	GHS07
Signal word	Warning
Hazard statements	H302
Personal Protective Equipment	dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes (Europe)	Xn
Risk Statements (Europe)	22
Safety Statements (Europe)	36
WGK Germany	3

Technical information & documentation associated with this product is available in the Safety & Documentation tab.

Articles

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.1 During the oxi...
BioFiles 2007, 2.2, 2.
Keywords: Adhesion, Anti-inflammatory agents, Cancer, Cardiovascular, Catalysis, Diabetes, Diseases, Gene expression, Metabolism, Neurodegenerative Diseases, Peroxidations, Phosphorylations, Prebiotics, Probiotics, Reductions, Transcription, Transduction, Vitamins

Fatty Acid Synthesis and Metabolism in Cancer Cells

Proliferatively active cells require fatty acids for functions such as membrane generation, protein modification, and bioenergetic requirements. These fatty acids are derived either from dietary sour...
Keywords: Apoptosis, Cancer, Carboxylations, Catalysis, Gene expression, Glycolysis, Metabolism, Oxidations, PAGE, Phosphorylations