Tunicamycin from Streptomyces sp.

Properties

Related Categories	AIDS and Viral Research Reagents, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics T-Z, Antibiotics by Application, Antifungal, Antineoplastic and Immunosuppressive Antibiotics, Antiviral, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Chemical Activators and Inhibitors of ER Stress, Chemical Structure Class, Endoplasmic Reticulum Stress, Glycobiology, Immune Cell Signaling and Blood, Immune System Regulation, Inhibitors, Inhibitors and Substrates, Interferes with Protein Synthesis, L - Z, Mechanism of Action, Nucleosides, Post-Translational Modification, Proteomics, Spectrum of Activity, T More...
Quality Level	PREMIUM
storage temp.	2-8°C

Description

Biochem/physiol Actions

Antibacterial and antifungal. Blocks the formation of protein N-glycosidic linkages by inhibiting the transfer of N-acetylglucosamine 1-phosphate to dolichol monophosphate. Inhibits bacterial and eukaryote N-acetylglucosamine transferases and prevents formation of N-acetylglucosamine lipid intermediates.

General description

Contains homologues A,B,C, and D. Composition may vary from lot to lot. Actual content given on label.

Price and Availability

Related Papers

Relationship of the structure and biological activity of the natural homologues of tunicamycin. Duksin, D. and Mahoney, W.C. J. Biol. Chem. 257, 3105-3109, (1982)

Documents

Certificate of Analysis

Certificate of Origin

Safety Information

Symbol	GHS06
Signal word	Danger
Hazard statements	H300
Precautionary statements	P264-P301 + P310
Personal Protective Equipment	Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Hazard Codes (Europe)	T+
Risk Statements (Europe)	28
Safety Statements (Europe)	28-37/39-45
RIDADR	UN 3462 6.1/PG 2
WGK Germany	3
RTECS	YO7980200

Technical information & documentation associated with this product is available in the Safety & Documentation tab.

Articles

Inhibition of Cell Wall Biosynthesis by Antibiotics

Antibiotics are molecules that specifically target and kill cells. The term antibiotic is frequently used interchangeably with the word antibacterial, but antiviral, antifungal and antineoplastic com...
BioFiles 2006, 1.4, 7.
Keywords: Antibiotics, Antifungals, Antivirals, Building blocks, Glycosylations, Metabolism