Synonym: Urate oxidase, Urate:O2 oxidoreductase
CAS Number 9002-12-4
EC Number 232-655-5
MDL number MFCD00082126
PubChem Substance ID 24900663
| Related Categories | 1.7.x.x Other nitrogenous donors, 1.x.x.x Oxidoreductases, Biochemicals and Reagents, Enzyme Class Index, Enzymes, Inhibitors, and Substrates, |
| form | lyophilized powder |
| storage temp. | −20°C |
One unit will convert 1.0 μmole of uric acid to allantoin per min at pH 9.0 at 25 °C.
Molecular weight: 4 × ~32 KDa (tetramer)
Isoelectric point: is 4.64
KM value (uric acid as substrate): ~ 0.01 mM
The optimum pH for activity: 8.5-9.5
The optimum pH for stability: 6.0-9.5
Zn and Cu were shown to inhibit the activity of uricase.
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