Synonym: Urate oxidase, Urate:O2 oxidoreductase
|Related Categories||1.7.x.x Other nitrogenous donors, 1.x.x.x Oxidoreductases, Biochemicals and Reagents, Enzyme Class Index, Enzymes, Inhibitors, and Substrates,|
One unit will convert 1.0 μmole of uric acid to allantoin per min at pH 9.0 at 25 °C.
Molecular weight: 4 × ~32 KDa (tetramer)
Isoelectric point: is 4.64
KM value (uric acid as substrate): ~ 0.01 mM
The optimum pH for activity: 8.5-9.5
The optimum pH for stability: 6.0-9.5
Zn and Cu were shown to inhibit the activity of uricase.
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