U7128 Sigma

Uricase from Arthrobacter globiformis

lyophilized powder, 15-30 units/mg protein (biuret)

DOWNLOAD MSDS (PDF)

Synonym: Urate oxidase, Urate:O2 oxidoreductase

Description

Unit Definition

One unit will convert 1.0 μmole of uric acid to allantoin per min at pH 9.0 at 25 °C.

Biochem/physiol Actions

Molecular weight: 4 × ~32 KDa (tetramer)
Isoelectric point: is 4.64
KM value (uric acid as substrate): ~ 0.01 mM
The optimum pH for activity: 8.5-9.5
The optimum pH for stability: 6.0-9.5

Zn and Cu were shown to inhibit the activity of uricase.

Price and Availability

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