A0228 Sigma

(Z)-Ajoene

oil

Synonym: (Z)-4,5,9-Trithiadodeca-1,6,11-triene-9-oxide

  • CAS Number 92285-01-3

  • Empirical Formula (Hill Notation) C9H14OS3

  • Molecular Weight 234.40

  •  MDL number MFCD06411561

Properties

form   oil
color   yellow
solubility   DMSO: <5 mg/mL
shipped in   wet ice
storage temp.   −20°C

Description

Application

Ajoene inhibits proliferation and induces apoptosis of several leukemic and non-leukemic cancer cell lines.

Biochem/physiol Actions

A sulfur-containing constituent of garlic with lipid-lowering, antithrombotic, and antiproliferative properties. Inhibits cholesterol and isoprenoid synthesis through inhibition of HMG-CoA reductase and the mevalonate pathway. It also inhibits protein prenylation required for cell proliferation.

Packaging

Packaged in ampules, under nitrogen

Price and Availability

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?